Long-Lasting Stability – Suspended in PEG-400 to ensure reliable solubility and shelf-life for research applications.
25mg/mL Concentration – A precisely measured liquid solution providing consistent results across studies.
Independently Verified – Third-party analysis confirms purity, concentration accuracy, and identity of every batch.
For Laboratory Research Only – Supplied strictly for scientific investigation, not for human consumption.
High-Quality Liquid MK-677 for Sale
MK-677, also known as Ibutamoren, Oratrope, or Nutrobal (molecular weight: 528.662), is a ghrelin agonist that acts on the pituitary gland as a human growth hormone secretagogue and is sometimes classified along with selective androgen receptor modulators (SARMs).
It differs from ghrelin itself in that it is not a peptide but rather a spiropiperidine. Since it can cross the blood-brain barrier, MK-677 functions as a neuropeptide in the central nervous system.
MK-677 vs. Other Growth Hormone Secretagogues
MK-677 is a potent hormone, and it is not uncommon to find it and other SARMs for sale in the same catalog. Data shows that MK-677 has an advantage over compounds like GHRP-6 and GHRP-2 in that it elevates IGF-1 levels for 24 hours after a single dose without inhibiting natural pulsatile growth hormone release.
Since it does not exert its effect via an androgen receptor, it is believed that MK-677 may improve body composition without negatively impacting endogenous androgen secretion, like testosterone and other anabolic compounds. Some data also suggests that MK-677 may have synergistic effects when combined with growth hormone-releasing peptides like Tesamorelin or Ipamorelin.
MK-677 FAQs
Studies have demonstrated the ability of MK-677 (aka Nutrobal) to raise endogenous levels of HGH and IGF-1.
There is presently no evidence that MK-677 compromises the body’s natural release of GH long-term. More information may be available in the future.
A two-year human study on MK-677 found that subjects experienced a significant decrease in the risk of developing gynecomastia compared to injectable growth hormone.
MK-677 does not act on the feedback loop for testosterone in the body and is not expected to suppress natural testosterone levels.
Data suggests that growth hormone secretagogues, like MK-677, may harm glucose tolerance and increase blood sugar levels with continuous testing.
The FDA has not approved MK‑677 (also known as Ibutamoren) for human consumption and remains classified as an investigational drug intended solely for scientific research.
MK‑677 remains under investigation; despite decades of research into its effects on growth hormone (GH), IGF‑1, body composition, and bone health, there is insufficient data on its long-term safety in healthy individuals. (Source)
Why choose Sports Technology Labs as the best place to buy MK-677?
A recent study involving chemical analyses of 44 different products sold and marketed as SARMs on the internet revealed that quality control in this industry varies significantly from one company to the next. Only 52% of the products tested contained the product advertised, 59% contained amounts that differed from the label, a shocking 39% contained other unapproved drugs, 25% contained substances not listed on the label, and 9% contained no active substance at all. Therefore, it is critical when performing research with SARMs to only purchase the highest quality compounds, verified by third-party analysis.
Many companies have Ibutamoren for sale, but Sports Technology Labs is the best place to buy MK-677 online because of our consistent, verifiable, high-quality products, safe bottling and packaging, fast shipping, and excellent customer service. We also have MK-677 Nutrobal available in pure powder form.
When you buy SARMs from Sports Technology Labs, you are choosing the highest quality ingredients. Minimum 98% pure compounds tested and certified by accredited American third-party labs, suspended in USP-grade (the highest grade) PEG-400, bottled in America. Our products come in glass bottles with fixed glass droppers to prevent the leaching of unwanted plasticizers like Bisphenol A (BPA), and to avoid contamination when using external measuring tools.
We run a transparent business, with no discreet payment methods necessary and no misrepresentation of our products, only the highest quality research chemicals available online, secured by our 60-day money-back guarantee.
We provide free shipping for orders exceeding $149, and for those who require expedited delivery, we also offer express shipping. Customers who subscribe to our email list enjoy a 10% discount and an extra 10% off when paying with cryptocurrency.
Not every company provides the highest quality MK-677. At Sports Technology Labs, you can buy the best Ibutamoren with confidence. We ship most orders the same day or the next day, offer free shipping for orders over $149, and guarantee quality and fresh products every time.
Do not compromise your research with low-quality or unverified products—shop with Sports Technology Labs. You are welcome to contact us with any questions you have about our MK-677 for sale.
Additional information
Weight
3.0 oz
Ibutamoren/MK-677
All Sports Technology Labs SARMs are third-party tested by MZ Biolabz, an independent laboratory based in Arizona. Each batch is bottled and tested in the USA to ensure accuracy and purity. Our Certificates of Analysis confirm that products meet the listed specifications:
When administered orally, MK-677 Ibutamoren mimics the action of the hunger hormone ghrelin and, by doing so, increases growth hormones (GHs) in the body. It is potent in boosting levels of insulin-like growth factor 1 (IGF-1).
Unlike growth hormone and most GH-increasing peptides, Ibutamoren is orally bioavailable, so it does not require injection for proper absorption. Sports Technology Labs is the best place to buy MK-677 online due to our verified high purity, fast shipping, customer support, and secure payment processing.
MK-677 Benefits in Clinical Research
MK‑677 (ibutamoren) is an investigational growth hormone secretagogue that has shown multiple effects in vivo, primarily by significantly increasing GH and IGF‑1 secretion levels observed in younger adults. (Source)
Increase in Muscle Mass and Lean Body Mass: A 12‑month study in older adults found that 25 mg/day MK‑677 significantly increased fat‑free mass (~1.1 kg vs. −0.5 kg with placebo) while enhancing GH and IGF‑1 secretion. (Source)
Reduced Body Fat: Research in older adults observed improvements in body composition, including favorable fat distribution and a relative reduction in visceral fat alongside higher metabolic turnover. (Source)
Increase in Bone Density: MK‑677 treatment was shown to elevate bone turnover markers and bone mineral density in older and osteoporotic subjects, potentially counteracting age‑related bone loss. (Source)
Accelerated Muscle Growth and Faster Recovery: The compound supports anabolic processes through enhanced GH‑IGF‑1 axis activation, promoting muscle protein synthesis and recovery in populations with muscle wasting or post-injury contexts (e.g., hip fracture recovery trials showed improved stair climbing and gait speed). (Source)
Improved Immune Function: Though less extensively studied, GH elevation is known to support immune health, and MK‑677’s stimulatory effects on GH/IGF‑1 are proposed to enhance immune response in elderly and GH‑deficient individuals (Source)
Improved REM Sleep: A small trial (14 subjects) reported that 25 mg of MK‑677 daily increased REM sleep by ~20–50% and slow-wave sleep (deep sleep) by ~50% in younger and older participants. (Source)
Increased Appetite: MK‑677 is known to induce orexigenic effects—increasing hunger and food intake—particularly in older adults, which can support nutritional intake and anabolic gains. (Source)
Reversal or Treatment of Growth Hormone Deficiency: In GH‑deficient children and adults, Ibutamoren has been shown to increase GH and IGF‑1 levels, sometimes outperforming standard secretagogues in pediatric trials (Source)
These findings reflect promising therapeutic avenues in clinical and preclinical research. However, it is important to note that most benefits have been observed in older adults, GH‑deficient individuals, or animal models—not in healthy populations—and long‑term safety and efficacy remain under ongoing investigation.
Studies Involving MK-677
Medical studies conducted in the last decade have shown significant potential for MK-677 to encourage REM sleep, increase GH levels, and build lean muscle mass. Several studies and clinical trials have been conducted that suggest MK-677 holds enormous promise as a drug that could enhance health and potentially aid in the battle against frailty in the elderly by mitigating symptoms of the natural decline of growth factors that come with aging, also known as somatopause. Studies have been conducted on both young males (aged 19-49) and individuals aged 60-81.
MK-677 and Growth Hormone Release
One study found that MK-677 administration increased IGF-I and IGF-binding protein-3 (IGFBP-3) levels, and potentially could be used to counter somatotropic deficiency and build muscle.
MK-677 and Body Composition
Another study found that MK-677 increased bone turnover, bone mineral density, muscle mass, and osteoblast activity in older adults and improved body composition.
A randomized controlled trial in healthy older adults found that daily 25 mg administration of MK-677 improved body composition, bone mineral density, and cholesterol levels, and stimulated appetite for several months.
A double-blind randomized controlled trial in healthy volunteers aged 24-39 on a calorie-restricted diet found that MK-677 significantly improved nitrogen retention even in an environment of negative nitrogen balance. This means that subjects maintained muscle mass even with a protein consumption considered less than sufficient. This may be of significant interest in the treatment of patients on parenteral nutrition or restricted to IV feeding.
MK-677 and Sleep Quality
A study on MK-677 and sleep quality revealed a significant decrease in REM latency and a 50% increase in REM sleep in older adults, as well as a 50% increase in stage 4 sleep and a 20% increase in REM sleep in young adults with the administration of MK-677. Stage 4 is the sleep stage in which the most tissue repair occurs, so this may be of significant interest in studies aimed at improving recovery and neurological function.
A placebo-controlled study involving both young and older adults found improvements in sleep quality when compared to the placebo after three separate seven-day administration trials.
MK-677 and Chronic Disease
Animal data suggest that MK-677 may be effective in reducing neuroinflammation, neurodegeneration, synapse loss, and slowing the early stages of beta amyloid buildup in the brain, a significant contributing factor for dementia and Alzheimer’s disease. The implications are that MK-677 may function as a preventative agent, not a curative agent, even in cases of genetic predisposition. More human data is necessary to confirm this.
Potential Side Effects of Ibutamoren
It must be emphasized that MK-677 has not been approved by the Food and Drug Administration (FDA) for human consumption or efficacy. The severity of documented side effects like water retention, angiogenesis, and changes in blood pressure and blood sugar is still being determined. Potential drug interactions are also unknown at this time, so caution is critical with this compound.
Since it has a very long half-life, there is some concern that sustained administration of MK-677 can overstimulate or desensitize the ghrelin receptor in the human brain. Perhaps the most immediately noticeable side effect of Ibutamoren at this time is a significant increase in appetite and hunger.
It is in the preclinical stages of investigation for GH deficiency and should be used for research purposes only. Further important research into MK-677 will be performed in the years to come.
Storage: Store in a cool, dry place away from direct sunlight to maximize shelf life.
30 mL of liquid MK-677 per bottle with 25 milligrams per milliliter.
Includes a graduated 1 mL glass pipette for convenient measurement.
Glass bottle with UV resistance to minimize degradation.
Tamper-proof seal to ensure safety in transit.
Less than 5% variance in concentration, guaranteeing consistency.
Formulated and packaged to prevent evaporation in storage.
SKU: 5
This preparation is a research chemical for laboratory research use only and is not approved by the FDA for human use. MK–677/Ibutamoren IS NOT A DIETARY OR SPORTS SUPPLEMENT.
Abuse Warning
MK-677 is an investigational compound still awaiting FDA approval and is not a dietary supplement. At Sports Technology Labs, we are chemical suppliers, not medical doctors, and our expertise is sourcing and quality control. Sports Technology Labs does not encourage or condone consumer use of SARMs products; they are for research purposes only.
SARMs should only be used under the supervision and direction of a medical doctor or designated research authority. We strongly discourage the use of SARMs for performance enhancement in sports and bodybuilding, and warn against “bro science” and peer consensus when making decisions about human health.
Scientific References:
1. G Copinschi, A Van Onderbergen, M L’Hermite-Balériaux, C M Mendel, A Caufriez, R Leproult, J A Bolognese, M De Smet, M O Thorner, E Van Cauter, Effects of a 7-day treatment with a novel, orally active, GH secretagogue, MK-677, on 24-hour GH profiles, IGF 1, and adrenocortical function in normal young men, The Journal of Clinical Endocrinology & Metabolism, Volume 81, Issue 8, 1 August 1996, Pages 2776–2782
2. Murphy MG, Bach MA, Plotkin D, Bolognese J, Ng J, Krupa D, et al. Oral administration of the growth hormone secretagogue MK-677 increases markers of bone turnover in healthy and functionally impaired elderly adults. The MK-677 Study Group. J Bone Miner Res. 1999;14:1182–1188L
3. Patchett AA, Nargund RP, Tata JR, Chen MH, Barakat KJ, Johnston DB, Cheng K, Chan WW, Butler B, Hickey G, et al. Design and biological activities of L-163,191 (MK-0677): a potent, orally active GH secretagogue. Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):7001-5. doi: 10.1073/pnas. 92.15.7001. PMID: 7624358; PMCID: PMC41459.
4. Meyer RM, Burgos-Robles A, Liu E, Correia SS, Goosens KA. A ghrelin-growth hormone axis drives stress-induced vulnerability to enhanced fear. Mol Psychiatry. 2014 Dec;19(12):1284-94. doi: 10.1038/mp. 2013.135. Epub 2013 Oct 15. PMID: 24126924; PMCID: PMC3988273.
6. Smith RG, Sun Y, Jiang H, Albarran-Zeckler R, Timchenko N. Ghrelin receptor (GHS-R1A) agonists show potential as interventive agents during aging. Ann N Y Acad Sci. 2007 Nov;1119:147-64. doi: 10.1196/annals. 1404.023. PMID: 18056963.
7. Nass R, Pezzoli SS, Oliveri MC, Patrie JT, Harrell FE Jr, Clasey JL, Heymsfield SB, Bach MA, Vance ML, Thorner MO. Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial. Ann Intern Med. 2008 Nov 4;149(9):601-11. doi: 10.7326/0003-4819-149-9-200811040-00003. PMID: 18981485; PMCID: PMC2757071.
8. Murphy MG, Plunkett LM, Gertz BJ, He W, Wittreich J, Polvino WM, Clemmons DR. MK-677, an orally active growth hormone secretagogue, reverses diet-induced catabolism. J Clin Endocrinol Metab. 1998 Feb;83(2):320-5. doi: 10.1210/jcem. 83.2.4551. PMID: 9467534.
9. Jeong YO, Shin SJ, Park JY, Ku BK, Song JS, Kim JJ, Jeon SG, Lee SM, Moon M. MK-0677, a Ghrelin Agonist, Alleviates Amyloid Beta-Related Pathology in 5XFAD Mice, an Animal Model of Alzheimer’s Disease. Int J Mol Sci. 2018 Jun 18;19(6):1800. doi: 10.3390/ijms19061800. PMID: 29912176; PMCID: PMC6032329.
10. Copinschi G, Leproult R, Van Onderbergen A, Caufriez A, Cole KY, Schilling LM, Mendel CM, De Lepeleire I, Bolognese JA, Van Cauter E. Prolonged oral treatment with MK-677, a novel growth hormone secretagogue, improves sleep quality in man. Neuroendocrinology. 1997 Oct;66(4):278-86. doi: 10.1159/000127249. PMID: 9349662.
11. Van Wagoner RM, Eichner A, Bhasin S, Deuster PA, Eichner D. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017 Nov 28;318(20):2004-2010.
