MK-677, also designated ibutamoren, MK-0677, or L-163,191, is a non-peptide growth hormone secretagogue and ghrelin receptor (GHS-R1a) agonist. Although it is often grouped with SARMs, it is structurally and mechanistically distinct and does not act on the androgen receptor. This listing is a research-grade reference compound supplied in powder form for in vitro and laboratory investigation. Every batch is third-party verified for identity and purity and accompanied by a downloadable Certificate of Analysis.
Identity and purity are independently confirmed by MZ Biolabs (Tucson, AZ), a US DEA Schedule III licensed analytical facility (License RP0584676). Each production batch undergoes HPLC purity analysis and mass-spectrometry identity confirmation under Good Laboratory Practice (GLP) standards to support research reproducibility.
Store in a cool, dry place away from direct sunlight to maximize shelf life. Supplied in a UV-resistant foil pouch to minimize photodegradation.
Independent analysis has repeatedly found that research compounds sold online are frequently mislabeled or adulterated. A 2017 JAMA investigation that chemically analyzed products marketed as SARMs, a category that included ibutamoren, found that only a minority accurately matched their labeled contents, and a substantial share contained unapproved or entirely different substances.[6] Batch-level third-party testing is the control that distinguishes a documented reference compound from an unverified one.
Ibutamoren was developed by Merck in the mid-1990s as a non-peptide mimetic of ghrelin, the endogenous ligand of the growth hormone secretagogue receptor (GHS-R1a).[1] Because it engages this receptor rather than the androgen receptor, it has become a common tool in studies of the growth hormone / insulin-like growth factor 1 (GH/IGF-1) axis. Published work includes pharmacodynamic studies characterizing 24-hour GH profiles and IGF-1 response,[2][3] investigations of bone-turnover markers,[4] and a two-year randomized, placebo-controlled trial in older adults examining body composition and clinical outcomes.[5] That literature also documents adverse findings, including changes in fasting glucose and insulin sensitivity.[5]
This material is supplied strictly as a reference compound to support such laboratory investigation. It is not a therapeutic product, dietary supplement, or sports supplement, and no clinical or performance outcomes are claimed or implied for any individual.
MK-677 (ibutamoren) is an investigational compound that has not been approved by the U.S. Food and Drug Administration for human use. It is not a dietary supplement, and marketing it for human ingestion is unlawful. It is supplied exclusively for laboratory research purposes.
For laboratory research use only. This preparation is not approved by the FDA for human use. MK-677 / ibutamoren is not a dietary or sports supplement and is not intended for human or animal consumption.
All products on this website are intended exclusively for research and development purposes. The statements herein have not been evaluated by the U.S. Food and Drug Administration. Neither the statements nor the products are intended to diagnose, treat, cure, or prevent any disease. Sports Technology Labs are chemical suppliers, not medical practitioners; our expertise is sourcing and quality control.
| Weight | 0.25 oz |
|---|---|
| Dimensions | 3 × 0.3 × 4 in |
