Andarine, more commonly known as S4 is the original SARM. Scientists discovered that while this molecule is not shaped like a steroid it does activate androgen receptors selectively in the body, favoring those in skeletal muscle, bone, and connective tissue over those in the scalp and prostate. This led to an explosion of research into molecules that selectively activate the androgen receptor (AR). S4 exerts its selectivity by having a higher binding affinity to these androgen receptors. In spite of being the first SARM developed, Andarine is still considered by many researchers to be one of the best SARMs for cutting bodyfat.
Rat studies reveal quantity-dependent improvements in bone health with administration of S4. In one study, 1.6mg/kg bodyweight showed significant improvements in bone mineral density, lean mass, and body composition. 3mg/kg/day demonstrated significant increases in muscle mass as well. In the ovariectomized rat model for osteoporosis, 3 and 10mg/kg/day were administered for 8 weeks and both groups showed improvements in whole body and trabecular bone mineral density, cortical content, and decreased body fat. Primary culture of bone marrow osteoprogenitor cells showed that S4 was more anabolic than DHT for promoting osteoblast formation, further confirming its anabolic potential in bone tissue.
Studies have also observed a decrease in prostate weight with similar efficacy to 5mg/kg finasteride administration without affecting levator and muscles (an indicator of relative androgenicity). This suggests that while SERMs are ideal candidates for reducing breast tissue and the spread of breast cancers, SARMs may hold the key to these types of benefits in situations of unwanted prostate growth.
S4 is the oldest and one of the most well studied SARMs but its side effects and severity are still being learned. It is reasonable to believe that some non-androgenic side effects of anabolic steroids such as increased hematocrit, insomnia, lethargy, and liver damage may result from the use or abuse of Andarine.
While anecdotal reports rank S4 as mild on side effects compared to other SARMs, it does have one side effect present at higher quantities that is unusual to other compounds and that is a temporary slight yellowing of the vision and reduction in night vision.
CAS Number: 401900-40-1
Molar Mass: 441.357
Class: Selective Androgen Receptor Modulator
Storage: Store in a cool dry place away from direct sunlight to maximize shelf life.
This preparation is for laboratory research purposes only and is not approved by the FDA for human use. S4/Andarine IS NOT A DIETARY OR SPORTS SUPPLEMENT.
S4, also known as Andarine, binds selectively to androgen receptors for tissue specific anabolic effects.
To date there are no studies demonstrating gynecomastia from Andarine / S4 however more data is needed.
Andarine may suppress natural testosterone production in male test subjects.
Data suggests that higher doses of S4 may temporarily worsen night blindness or cause a benign yellowish tint to vision in test subjects. These effects discontinue quickly after cessation.
If you’re trying to figure out where to buy S4 online, there certainly seem to be plenty of choices out there. Sports Technology Labs is the best place to buy Andarine online because of their consistent, verifiable high quality products, safe bottling and packaging, fast shipping, and great customer service. Our Andarine is also available in pure powder form. Not all companies offering S4 for sale are alike—or equally trustworthy. To buy S4 from a randomly selected website is dangerous, even if the price looks reasonable, because you can’t be certain about their quality-control processes. At Sports Technology Labs you can find the highest quality SARMs for sale anywhere on the internet.
When you buy SARMs from Sports Technology Labs you are choosing the highest quality ingredients. Minimum 98% pure compounds tested and certified by accredited American third party labs, suspended in USP grade (the highest grade) PEG400, bottled in America. Our products come in glass bottles with fixed glass droppers to prevent the leaching of unwanted plasticizers like BPA, and prevent contamination between testing with external measuring tools.
We run a transparent business, with no discreet payment methods necessary and no misrepresentation of our products, only the highest quality research chemicals available online, secured by our 60-day money-back guarantee. For orders totaling $149 or more, we offer free shipping. If you’re in a hurry to receive your products, we also provide express shipping options. Additionally, customers who sign up for our email list receive a 10% discount, and an additional 10% off when paying with cryptocurrency.
That’s why we’re confident in our claim that we offer the best Andarine for sale on the market today. If you have any questions about our liquid S4 products, you can also contact us and we’ll respond as soon as possible.
S4 is an investigational compound still awaiting FDA approval and is not a dietary supplement. At Sports Technology Labs we are chemical suppliers, not medical doctors, and our expertise is sourcing and quality control. Sports Technology Labs does not encourage or condone consumer use of SARMs products, they are for research purposes only.
SARMs should only be used under the supervision and direction of a medical doctor or designated research authority. We strongly discourage the use of SARMs for performance enhancement in sports and bodybuilding, and warn against “bro science” and peer consensus when making decisions about human health.
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4. Gao W, Kearbey JD, Nair VA, Chung K, Parlow AF, Miller DD, Dalton JT. Comparison of the pharmacological effects of a novel selective androgen receptor modulator, the 5alpha-reductase inhibitor finasteride, and the antiandrogen hydroxyflutamide in intact rats: new approach for benign prostate hyperplasia. Endocrinology. 2004;145:5420–5428
5. Burmeister M, Graham W. Recreational use of Selective Androgen Receptor Modulators. US Pharm;2020;45(60):15-18.