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RAD-140 Powder (Testolone) | 2 Grams

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$102.99

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Description

Research-Grade SARM Reference Material

RAD-140 (Testolone) Powder — 2 Grams

RAD-140, also designated testolone or vosilasarm, is a non-steroidal selective androgen receptor modulator (SARM) originally developed by Radius Health as an investigational compound. This listing is a research-grade reference compound supplied in powder form for in vitro and laboratory investigation. Identity and purity are third-party verified and documented by a downloadable Certificate of Analysis.

  • 97.47% purity (HPLC)
  • Third-party verified
  • 2,050 mg net
  • Public COA
  • UV-resistant foil pouch
Technical Reference

Specifications & Documentation

Compound
RAD-140 (Testolone / Vosilasarm)
IUPAC Name
2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile
CAS Number
1182367-47-0
Molecular Formula
C₂₀H₁₆ClN₅O₂
Molar Mass
393.83 g/mol
Compound Class
Selective Androgen Receptor Modulator (SARM) · Non-steroidal
WADA Classification
Prohibited — Class S1.2 (Other Anabolic Agents)
Form
Crystalline powder
Net Quantity
2,050 mg per pouch
Verified Purity
97.47% by HPLC–UV–MS (current COA)
Why Verification Matters

Quality & Analytical Transparency

Independent analysis has repeatedly found that materials sold online as SARMs are frequently mislabeled or adulterated. A 2017 JAMA investigation that chemically analyzed products marketed as SARMs found that only a minority accurately matched their labeled contents, and a substantial share contained unapproved or entirely different substances.[6] Third-party testing is the control that distinguishes a documented reference compound from an unverified one.

97.47%HPLC Purity
HPLCPurity Method
MSIdentity Confirmation
GLPTesting Standard
Scientific Background

Research Context

RAD-140 was developed by Radius Health as a non-steroidal SARM with high androgen receptor binding affinity and tissue-selective activity. Its original preclinical characterization, including studies in rodents and non-human primates, was published in 2011.[1] Subsequent laboratory work examined androgen receptor activity in cultured neurons and a kainate-lesioned rat model,[2] as well as androgen/estrogen receptor–positive breast cancer models.[3] A first-in-human Phase I study in patients with ER+/HER2– metastatic breast cancer reported pharmacokinetic and safety data, with liver enzyme elevations among the adverse events observed.[4] Case reports have also described drug-induced liver injury associated with SARM products.[5]

This material is supplied strictly as a reference compound to support such laboratory investigation. It is not a therapeutic product, dietary supplement, or sports supplement, and no clinical or performance outcomes are claimed or implied for any individual.

Regulatory Status

Compliance & Legal Status

RAD-140 (testolone) is an investigational compound that has not been approved by the U.S. Food and Drug Administration for human use. It is not a dietary supplement, and marketing it for human ingestion is unlawful. It is supplied exclusively for laboratory research purposes.

FDA StatusNot approved for human use; not a dietary or sports supplement.
WADA StatusProhibited at all times — Class S1.2, Other Anabolic Agents.[7]
Intended UseLaboratory / in vitro research reference material only.
Not ForHuman or animal consumption, diagnosis, treatment, or performance use.
Citations

Scientific References

  1. Miller CP, Shomali M, Lyttle CR, et al. Design, synthesis, and preclinical characterization of the selective androgen receptor modulator (SARM) RAD140. ACS Med Chem Lett. 2011;2(2):124–129.
  2. Jayaraman A, Christensen A, Moser VA, et al. Selective androgen receptor modulator RAD140 is neuroprotective in cultured neurons and kainate-lesioned male rats. Endocrinology. 2014;155(4):1398–1406.
  3. Yu Z, He S, Wang D, et al. Selective androgen receptor modulator RAD140 inhibits the growth of androgen/estrogen receptor–positive breast cancer models with a distinct mechanism of action. Clin Cancer Res. 2017;23(24):7608–7620.
  4. LoRusso P, Hamilton E, Ma C, et al. A first-in-human phase 1 study of a novel selective androgen receptor modulator (SARM), RAD140, in ER+/HER2– metastatic breast cancer. Clin Breast Cancer. 2022;22(1):67–77.
  5. Flores JE, Chitturi S, Walker S. Drug-induced liver injury by selective androgenic receptor modulators. Hepatol Commun. 2020;4(3):450–452.
  6. Van Wagoner RM, Eichner A, Bhasin S, Deuster PA, Eichner D. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017;318(20):2004–2010.
  7. World Anti-Doping Agency. The Prohibited List, Section S1.2: Other Anabolic Agents. WADA.org.

Research Disclaimer

For laboratory research use only. This preparation is not approved by the FDA for human use. RAD-140 / testolone is not a dietary or sports supplement and is not intended for human or animal consumption.

All products on this website are intended exclusively for research and development purposes. The statements herein have not been evaluated by the U.S. Food and Drug Administration. Neither the statements nor the products are intended to diagnose, treat, cure, or prevent any disease. Sports Technology Labs are chemical suppliers, not medical practitioners; our expertise is sourcing and quality control.

Additional information

Weight 0.25 oz
Dimensions 3 × 0.3 × 4 in

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