Description
LGD-4033 (Ligandrol) Powder — 2 Grams
LGD-4033, also designated ligandrol or VK5211, is a non-steroidal selective androgen receptor modulator (SARM) originally developed by Ligand Pharmaceuticals as an investigational compound. This listing is a research-grade reference compound supplied in powder form for in vitro and laboratory investigation. Identity and purity are third-party verified and documented by a downloadable Certificate of Analysis.
- 97.25% purity (HPLC)
- Third-party verified
- 2,050 mg net
- Public COA
- UV-resistant foil pouch
Specifications & Documentation
- Compound
- LGD-4033 (Ligandrol / VK5211)
- IUPAC Name
- 4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile
- CAS Number
- 1165910-22-4
- Molecular Formula
- C₁₄H₁₂F₆N₂O
- Molar Mass
- 338.26 g/mol
- Compound Class
- Selective Androgen Receptor Modulator (SARM) · Non-steroidal
- WADA Classification
- Prohibited — Class S1.2 (Other Anabolic Agents)
- Form
- Crystalline powder
- Net Quantity
- 2,050 mg per pouch
- Verified Purity
- 97.25% by HPLC (current COA)
Third-Party Verification
Identity and purity are independently confirmed by MZ Biolabs (Tucson, AZ), a US DEA Schedule III licensed analytical facility (License RP0584676), using HPLC purity analysis and mass-spectrometry identity confirmation under Good Laboratory Practice (GLP) standards to support research reproducibility.
- Latest COA Date
- [MM/DD/YYYY]
- Reported Purity
- 97.25%
- Methods
- HPLC–UV purity; MS identity confirmation
- Verifying Lab
- MZ Biolabs, Tucson, AZ (DEA Schedule III, RP0584676)
Current certificate of analysis for LGD-4033, issued by MZ Biolabs. Tap to view full size.
Open or download the current LGD-4033 COA · View the full COA archive →
Storage & Handling
Store in a cool, dry place away from direct sunlight to maximize shelf life. Supplied in a UV-resistant foil pouch to minimize photodegradation.
- Packaging
- UV-resistant sealed foil pouch
- Storage
- Cool, dry, dark; away from direct sunlight
- Handling
- Standard laboratory PPE and analytical-grade equipment
- Intended Use
- Laboratory and in vitro research only
Quality & Analytical Transparency
Independent analysis has repeatedly found that materials sold online as SARMs are frequently mislabeled or adulterated. A 2017 JAMA investigation that chemically analyzed products marketed as SARMs found that only a minority accurately matched their labeled contents, and a substantial share contained unapproved or entirely different substances.[4] Third-party testing is the control that distinguishes a documented reference compound from an unverified one.
Research Context
LGD-4033 was developed by Ligand Pharmaceuticals as a non-steroidal SARM that binds the androgen receptor with high affinity and tissue-selective activity, and was later licensed for clinical development as VK5211. A published Phase I study in healthy young men characterized its safety and pharmacokinetic profile and also reported dose-dependent suppression of total testosterone, sex hormone–binding globulin, and HDL cholesterol.[1] The compound was subsequently evaluated in a Phase II trial in patients recovering from hip fracture.[3] Its metabolic fate has been studied extensively in anti-doping research to support detection methods.[2]
This material is supplied strictly as a reference compound to support such laboratory investigation. It is not a therapeutic product, dietary supplement, or sports supplement, and no clinical or performance outcomes are claimed or implied for any individual.
Compliance & Legal Status
LGD-4033 (ligandrol) is an investigational compound that has not been approved by the U.S. Food and Drug Administration for human use. It is not a dietary supplement, and marketing it for human ingestion is unlawful. It is supplied exclusively for laboratory research purposes.
Scientific References
- Basaria S, Collins L, Dillon EL, et al. The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men. J Gerontol A Biol Sci Med Sci. 2013;68(1):87–95.
- Fragkaki AG, Sakellariou P, Kiousi P, et al. Human in vivo metabolism study of LGD-4033. Drug Test Anal. 2018;10(11–12):1635–1645.
- Viking Therapeutics. Viking Therapeutics initiates Phase 2 trial of VK5211 in patients recovering from hip fracture [press release]. PR Newswire; November 2015.
- Van Wagoner RM, Eichner A, Bhasin S, Deuster PA, Eichner D. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017;318(20):2004–2010.
- World Anti-Doping Agency. The Prohibited List, Section S1.2: Other Anabolic Agents. WADA.org.
Research Disclaimer
For laboratory research use only. This preparation is not approved by the FDA for human use. LGD-4033 / ligandrol is not a dietary or sports supplement and is not intended for human or animal consumption.
All products on this website are intended exclusively for research and development purposes. The statements herein have not been evaluated by the U.S. Food and Drug Administration. Neither the statements nor the products are intended to diagnose, treat, cure, or prevent any disease. Sports Technology Labs are chemical suppliers, not medical practitioners; our expertise is sourcing and quality control.



