Specifications Transparency: Clear labeling and documentation for methodical study design and reporting.TB-500 For Sale Online
High Purity (≥99%): Each lot is analyzed by an independent laboratory (HPLC/MS) for identity, potency, and purity.
Batch COA Access: Third-party testing results are batch-linked to support reproducible research.
Research-Grade Packaging: Lyophilized in UV-resistant glass, with tamper-evident seals.
TB-500 is a 43 43-amino-acid synthetic peptide analog of the active region of thymosin beta-4 (Tβ4), a naturally occurring protein widely distributed in mammalian tissues. Tβ4 has been investigated in in vitro systems and animal models for its involvement in cell migration, tissue repair, wound healing, angiogenesis (formation of new blood vessels), and inflammation modulation within damaged tissues.
All content here reflects preclinical research (e.g., rodent and other animal studies) and does not constitute evidence of safety or efficacy for human use.
Quantity: 5 mg lyophilized peptide per sterile glass vial
**Intended Use:**In vitro or controlled in vivo laboratory research by qualified professionals
In preclinical studies, TB-500/Tβ4 has been explored in a variety of systems, including cardiac, renal, neurological, and connective tissues. Across multiple animal models, thymosin beta-4 and its analogs have been associated with:
Enhanced wound healing parameters and angiogenesis
Tendon, ligament, and muscle tissue repair and regeneration endpoints
Spinal cord and neurotrauma models, with observed functional improvements in animals
Investigations into renal and hepatic disease progression pathways in rodents
TB-500 has been studied with particular interest in areas such as spinal cord injury, bone repair, tendon and ligament healing, and muscle regeneration in preclinical models. These findings are specific to laboratory research contexts and do not imply any approved medical use or human
TB-500 vs. Other Peptides
Feature
TB-500
BPC-157
Thymosin Alpha-1
Source
Synthetic analog of TB-4
Gastric peptide fragment
Thymus-derived peptide
Key Mechanism of Action
Binds actin, promotes cell migration, proliferation, and differentiation
Modulates immune system function, gene expression, and hormone regulation
Transparent Labeling & Docs: Clear specifications for study planning and reporting.
Secure Fulfillment: Tamper-evident packaging and reliable logistics.
Support: Responsive customer service for documentation and product questions.
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At Sports Technology Labs, you can find the highest quality TB-500 thymosin beta 4 for sale anywhere on the internet.
When you buy peptides from Sports Technology Labs, you are choosing the highest quality products. Pure compounds are tested and certified by accredited American third-party labs that accept phone calls to verify the validity of their certificates. Our products are lyophilized in glass bottles and are stored in refrigeration to prevent degradation.
We run a transparent business, with no discreet payment methods necessary and no misrepresentation of our products, only the highest quality research chemicals available online, secured by our 60-day money-back guarantee. We offer free shipping on orders over $149, and if you need the products in a hurry, we offer express shipping as well. Customers who sign up for our email list get 10% off, and an additional 10% off for payment with cryptocurrency.
Sports Technology Labs is the best place to buy TB-500 peptide online because of our consistent, verifiable, high-quality products, safe bottling and packaging, fast shipping, and excellent customer service. And if you have any questions about our TB-500 Thymosin β4 and other products, you can also contact us, and we’ll respond as soon as possible.
Additional information
Weight
0.25 oz
Dimensions
2 × 1 × 1 in
TB-500
All Sports Technology Labs peptides are third-party tested by MZ Biolabs, an independent laboratory based in Arizona. While not bottled in the USA, every batch is tested here to verify accuracy and purity. Our Certificates of Analysis confirm that products meet the listed specifications.
Published animal models and in vitro studies have explored TB-500/Tβ4 in several preclinical research domains:
Wound Healing & Tissue Repair: Experimental endpoints have included re-epithelialization, injury recovery kinetics, cell migration assays (e.g., scratch/wound models), and other markers of tissue regeneration. In rodent studies, TB-500 has been associated with accelerated wound closure and changes in cellular migration dynamics.
Skeletal Muscle & Connective Tissue: Preclinical work has focused on tendon, ligament, and muscle models, evaluating matrix organization, collagen deposition, and mechanical strength (e.g., peak force to failure in mouse fracture models). Some studies have examined inflammation markers and functional endpoints related to tissue regeneration in animals.
Vascular & Cardiac Models: Investigations have focused on angiogenic effects and myocardial repair in animal models, including measurements of blood vessel density and perfusion in injured rodent tissues.
Neurotrauma Models: Animal studies of spinal cord injury and traumatic brain injury have examined indices of cellular repair, myelination markers, and functional outcomes in controlled laboratory settings.
Ocular Surface & Corneal Models: Preclinical research has investigated corneal epithelial repair, tear-film stability, and ocular surface healing following injury.
Inflammation Modulation: Rodent studies have explored the regulation of local inflammatory cytokines as a mechanistic endpoint.
These domains represent areas of active preclinical investigation, particularly within fields related to tissue regeneration and sports medicine research. TB-500 is supplied exclusively for in vitro or controlled in vivo laboratory research and is not approved for human use.
TB-500 and Peripheral Tissue Healing
In an animal model, mice that were given TB-500 showed much stronger healed fractures and blood vessels than the control group. The Mice treated with TB-500 thymosin Beta 4 had an increase in peak force to failure as well as improved connective tissue repair. After the mice were treated with TB-500 post-fracture, imaging showed substantial improvement in wound healing compared to subjects who did not receive TB-500, less scar tissue, and an increase in trabecular bone area.
This suggests that the TB-500 thymosin beta promoted the repair and regeneration of blood cells and connective tissue, as well as faster bone and muscle healing with fewer complications.
TB-500 Peptide and Kidney Health
Another study in mice suggested that low natural levels of Thymosin Beta 4 or TB-500 might accelerate the progression of known kidney disease. This correlation suggests that the body’s natural thymosin Beta 4, present in healthy individuals, may protect the kidney and potentially reduce the progression of kidney disease in animal cells. This may be due to the tendency of TB-500 to promote the growth of new blood vessels, an effect that may be mediated by growth factors involved in tissue repair and regeneration.
TB-500 and Nervous System Repair
TB-500’s effects on the spinal cord and traumatic brain injury have been studied in rats with potential applicability to repair and regenerate mammals. In one study, TB-500 was administered to rats after inducing spinal cord injury. The rats that received the TB-500 treatment showed significant improvements in their locomotor skills and behavior when compared to the control group of rats. The levels of inflammatory cytokines were reduced, the size of scars was markedly reduced, and levels of myelin proteins were increased above those in the control group.
TB-500 has also been shown to improve brain function after a traumatic brain injury (TBI). In rat studies, TB-500 has been shown to promote cell migration, form new blood vessel growth, create new brain cells, and establish new connections between existing brain cells.
TB-500 and Eye Health
A recent study observed the effects of TB-500 thymosin Beta 4 on subjects with diabetic retinopathy. After administering TB-500 eye drops to test subjects, researchers found that recovery time was significantly reduced following surgery. Corneas from test subjects affected by diabetic retinopathy contained less thymosin Beta 4 or TB-500 than healthy corneas. In addition to this main group of test subjects, those suffering from chronic dry eye were given thymosin Beta 4 synthetic version TB-500 eye drops and noted an improvement in symptoms, with very few complications.
Anti-Inflammatory and Cellular Repair
TB-500 thymosin Beta 4 showed acceleration in recovery from burns, diabetic ulcers, pressure ulcers, stasis ulcers, and epidermolysis wounds in subjects. TB-500 thymosin Beta 4 is known to promote muscle cell growth and mitochondrial RNA replication. TB-500 thymosin beta promotes cell building protein and reduces inflammation and has been shown to help regenerate muscle fibers and address inflammation in the injured location, providing accelerated muscle regeneration.
Known mechanisms for this effect include, but are not limited to, improvement in blood cell and blood vessel formation, anti-inflammatory activity, and increased platelet aggregation at wound sites.
Note: Phrases such as “muscle recovery,” “post-surgical healing,” “improve flexibility,” or “enhancing physical capabilities” frequently appear in non-academic discussions. Sports Technology Labs does not make or endorse human-use claims. All information presented reflects preclinical research and should not be interpreted as evidence of clinical safety or efficacy.
Mechanism of Action (Preclinical)
In preclinical literature, Tβ4/TB-500 is reported to interact with the actin cytoskeleton, facilitating cellular repair programs relevant to tissue regeneration:
Actin Binding & Cytoskeletal Dynamics: Association with G-actin has been linked to cell migration and cellular remodeling in experimental systems (a core process in the healing process observed in animal models).
Angiogenesis & Vascular Response: Studies describe pro-angiogenic signaling and growth factor interplay (e.g., VEGF-related pathways) that may increase blood flow to experimental injury sites by promoting new blood vessels formation.
Extracellular Matrix Remodeling: Reports of increased collagen synthesis and matrix organization correlate with connective-tissue and tendon endpoints in animal studies.
Inflammation Modulation: Multiple models note anti-inflammatory properties (reduced local inflammatory markers and oxidative stress), consistent with tissue repair readouts in rodent systems.
TB-500, a synthetic version of Thymosin Beta-4 (TB-4), promotes healing by binding to actin, a protein crucial for cell movement and structure. This interaction facilitates cell migration, proliferation, and differentiation, making it particularly effective in tissue repair and angiogenesis (formation of new blood vessels). (Source)
TB-500’s low molecular weight allows it to travel long distances through tissues, targeting areas of injury more efficiently than many other peptides. It is often used in research exploring myocardial (heart) repair, wound healing, and inflammation control.
Important: These mechanistic observations are model-dependent and context-specific. They do not imply clinical efficacy, performance enhancement, or optimal health outcomes in humans.
Third-Party Tested: Every lot is verified by an independent U.S. laboratory for identity, purity, and concentration.
UV-Resistant Glass: Helps protect photo-labile peptides during storage.
Tamper-Evident Seals: Support chain-of-custody and inventory controls.
Documentation:Certificate of Analysis (COA), label transparency, and batch-linked traceability.
Abuse Warning
This preparation is for in vitro laboratory research purposes only by licensed professionals and is not approved by the FDA for bodily introduction of any kind into humans or animals. TB-500 is not a drug, food, supplement, or cosmetic and may not be misbranded, misused, or mislabeled as a drug, food, supplement, or cosmetic.
Regulatory and Anti-Doping Notice
Not for Human Use: TB-500 is not FDA-approved and is not a drug, food, dietary supplement, cosmetic, or peptide therapy product.
Anti-Doping: Thymosin beta-4–related substances are prohibited by the World Anti-Doping Agency (WADA). Use in sport may constitute a violation and lead to sanctions if tested positive.
Compliance: Researchers are responsible for compliance with local laws, institutional policies, and regulatory status in their jurisdiction.
1. Is TB-500 the same as thymosin beta-4?
TB-500 is a synthetic peptide modeled on the active region of thymosin beta-4. It is supplied as a research chemical to study Tβ4-related biology in experimental models.
2. Can you provide dosing or “appropriate dosage” guidance?
No. Sports Technology Labs does not provide dosing, cycle, or peptide therapy guidance. TB-500 is for laboratory research only, not for human use.
3. How should TB-500 be stored and handled?
Store lyophilized peptide cool, dry, and protected from light. After reconstitution with a suitable laboratory diluent, refrigerate and follow your institution’s SOPs for handling, aliquoting, and disposal.
4. Can TB-500 be combined with other peptides (e.g., BPC-157) in studies?
Some animal studies explore combination paradigms (e.g., with BPC-157) for tissue repair endpoints. Any co-administration should follow your IACUC/ethical approvals and experimental design. No human-use guidance is provided.
5. Is TB-500 allowed in sports?
Thymosin beta-4–related agents are prohibited by WADA and many sports organizations. This product is not for athletes or performance enhancement; it is for research.
6. What are the potential risks discussed in the literature?
Preclinical and review literature discuss theoretical risks related to angiogenesis, immune modulation, and general unknowns due to limited clinical data. This underscores the need for controlled lab use only. Sports Technology Labs does not provide medical advice.
7. What is TB-500 used for?
TB-500 is a peptide that is being researched for its regenerative effects in a variety of tissues, including muscle, connective tissue, and bone. It is also the subject of studies on a variety of inflammatory, cardiovascular, and neurological conditions.
8. Is TB-500 peptide better than BPC-157?
TB-500 has demonstrated greater efficacy in the regeneration of peripheral tissues, including muscle and connective tissue, while BPC-157 is considered more effective in the healing of the gastrointestinal tract.
9. What is the difference between TB-500 and BPC-157?
TB-500 is a synthetic analog of Thymosin Beta, a healing peptide that is naturally secreted by the thymus gland. BPC-157 is a modified section of Body Protection Compound, a healing peptide naturally produced in the stomach.
Scientific References:
1. Tokura Y, Nakayama Y, Fukada S, Nara N, Yamamoto H, Matsuda R, Hara T. Muscle injury-induced thymosin β4 acts as a chemoattractant for myoblasts. J Biochem. 2011 Jan;149(1):43-8. doi: 10.1093/jb/mvq115. Epub 2010 Sep 29. PMID: 20880960.
3. Vasilopoulou E, Kolatsi-Joannou M, Lindenmeyer MT, White KE, Robson MG, Cohen CD, Sebire NJ, Riley PR, Winyard PJ, Long DA. Loss of endogenous thymosin β4 accelerates glomerular disease. Kidney Int. 2016 Nov;90(5):1056-1070. doi: 10.1016/j.kint.2016.06.032. Epub 2016 Aug 26. PMID: 27575556; PMCID: PMC5073078.
4. Kleinman HK, Sosne G. Thymosin β4 Promotes Dermal Healing. Vitam Horm. 2016;102:251-75. doi: 10.1016/bs.vh.2016.04.005. Epub 2016 May 24. PMID: 27450738.
5. Goldstein AL, Kleinman HK. Advances in the basic and clinical applications of thymosin β4. Expert Opin Biol Ther. 2015;15 Suppl 1:S139-45. doi: 10.1517/14712598.2015.1011617. Epub 2015 Jun 22. PMID: 26096726.
7. Cheng P, Kuang F, Zhang H, Ju G, Wang J. Beneficial effects of thymosin β4 on spinal cord injury in the rat. Neuropharmacology. 2014 Oct;85:408-16. doi: 10.1016/j.neuropharm.2014.06.004. Epub 2014 Jun 14. PMID: 24937047.
8. Xiong Y, Mahmood A, Meng Y, Zhang Y, Zhang ZG, Morris DC, Chopp M. Neuroprotective and neurorestorative effects of thymosin β4 treatment following experimental traumatic brain injury. Ann N Y Acad Sci. 2012 Oct;1270:51-8. Doi: 10.1111/j.1749-6632.2012.06683.x. PMID: 23050817; PMCID: PMC3547647.
