Melanotan II (MT-2), a synthetic version of human alpha melanocyte stimulating hormone (αMSH), has displayed several recorded benefits including increased sexual arousal, improved tanning or skin pigmentation (melanogenesis), reduction in compulsive behavior, assistance with addiction control, appetite control and help with weight loss, and some data suggests mitigation in signs of Autism.
Melanotan II FAQs
Both forms of Melanotan increase eumelanin content and accelerate melanogenesis. Melanotan II also contributes to erection quality and sex drive. PT-141 peptide, also known as Bremelanotide, is a variation of Melanotan II designed explicitly for sexual benefits.
Melanotan accelerates the production of melanin, the pigment that gives skin its color and protects the skin against ultraviolet radiation. This effect is temporary.
Due to its tendency to increase replication of melanocytes, there is concern that melanotan II may increase the risk of Melanoma, although it does not cause sunburn-like inflammation.
Why Buy Melanotan II From Sports Technology Labs?
If you want to buy Melanotan II, it’s not hard to find a seller. Still, Sports Technology Labs is the best place to buy Melanotan II online because of their consistent, verifiable, high-quality product, fast shipping, and excellent customer service. A quick search will uncover plenty of Melanotan II reviews from companies that specialize in peptides. But the simple truth is that buying MT2 peptide from an obscure website is risky; not all companies selling peptides like Melanotan II are trustworthy.
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Most companies with peptides for sale, sad to say, do not test their products, or hide their certificates or contact information for their third-party labs from customers.
At Sports Technology Labs, you can find the highest quality Melanotan for sale anywhere on the internet. When you buy peptides from Sports Technology Labs, you are choosing the highest quality products. Pure compounds are tested and certified by accredited American third-party labs that accept phone calls to verify the validity of their certificates. Our products come lyophilized in glass bottles and are stored in refrigeration to prevent degradation and preserve shelf life.
We run a transparent business, with no discreet payment methods necessary and no misrepresentation of our products, only the highest quality research chemicals available online, secured by our 60-day money-back guarantee. That is why we are confident in our claim that Sports Technology Labs has the best Melanotan II for sale.
We provide free shipping for orders exceeding $149, and for those who require expedited delivery, we also offer express shipping. Customers who subscribe to our email list enjoy a 10% discount and an extra 10% off when paying with cryptocurrency. If you have any questions about our Melanotan II for sale for laboratory research use, please don’t hesitate to contact us.
Additional information
Weight
0.25 oz
Dimensions
2 × 1 × 1 in
Melanotan II
All Sports Technology Labs peptides are third-party tested by MZ Biolabs, an independent laboratory based in Arizona. While not bottled in the USA, every batch is tested here to verify accuracy and purity. Our Certificates of Analysis confirm that products meet the listed specifications.
Melanotan has demonstrated significant effects on melanin production (melanogenesis), also known as “sunless tanning” or skin tanning without sun exposure. It does so by binding primarily to MC-1R and MC-4R, and has lesser effects in MC-3R, three of the five melanocortin receptors in the body. MC-1R is found in melanocytes in the skin and is primarily involved in the darkening of the skin, and helps the skin produce melanin. In contrast, MC-3R is involved in appetite and impulse control, and MC-4R is involved in sexual arousal, libido, and male erectile functionality.
It is critical to note that long-term side effects of sunless tanning, including the use of melanotan II peptides, have not been established, and that treatment with prolific agents like MT-2 may potentially stimulate the proliferation of existing skin cancer.
Melanotan II and Receptor Expression
MT-2 was found to decrease fat storage and hunger behavior in animal models. Research suggests that MT-2 has similar effects to the hormone leptin and could be effective for reducing hunger by stimulating both leptin-dependent and leptin-independent pathways. Both MT-2 and leptin are thought to cause an increase in thyrotropin-releasing hormone (TRH) gene expression and the MC-4R pathway, stimulating a region of the brain associated with satiety and food intake.
MT-2 is one of the very few substances that cross into the central nervous system in sufficient quantities to have an effect on TRH expression. Mice given Melanotan II demonstrated minimal affinity for dietary fat and satiety with lower caloric intake.
Melanotan II and Impulse Control/Addiction
MT-2 might play a role in impulse control by affecting oxytocin signaling. Studies have shown in rats that prefer alcohol that administration of MT-2 reduces alcohol intake and increases water intake. Melanotan II also works synergistically with Naltrexone to reduce alcohol consumption several-fold. More research is needed in this potential avenue for Melanotan therapy.
Melanotan II and the Features of Autism
In a common mouse model of Autism Spectrum Disorder (ASD), administration of MT-2 reversed certain features of Autism. The research showed that MT-2 administration increased oxytocin receptor expression, communication, and social interaction, while decreasing repetitive behaviors associated with ASD. This suggests a direct correlation between oxytocin signaling in the brain and ASD behavior.
Melanotan II Libido and Erectile Dysfunction
MT-2 has demonstrated efficacy in treatment for ED that has been shown to work in 80% of cases of failed treatment with other ED medications. MT-2 has also been investigated as a treatment for both male and female sexual desire disorders and may improve libido and sexual arousal. Recent research suggests that MT-2 can have even more wide-ranging applications than other ED drugs due to its actions in the central nervous system, and not just vasodilation.
Melanotan and Dementia
Research on Alzheimer’s disease indicates that Melanotan II peptides may reduce beta amyloid accumulation and decrease the A1 subtype of reactive astrocytes, which are believed to contribute heavily to neurotoxicity and neuron death in Alzheimer’s Disease. More research is needed to establish a definitive link between Melanotan and dementia.
This preparation is for in vitro laboratory research purposes only by licensed professionals and is not approved by the FDA for bodily introduction of any kind into humans or animals. Melanotan II is not a drug, food, supplement, or cosmetic and may not be misbranded, misused, or mislabeled as a drug, food, supplement, or cosmetic.
Scientific References:
1. Minakova E, Lang J, Medel-Matus JS, Gould GG, Reynolds A, Shin D, Mazarati A, Sankar R. Melanotan-II reverses autistic features in a maternal immune activation mouse model of autism. PLoS One. 2019 Jan 10;14(1):e0210389. doi: 10.1371/journal.pone.0210389. PMID: 30629642; PMCID: PMC6328175.
2. Shimizu H, Inoue K, Mori M. The leptin-dependent and -independent melanocortin signaling system: regulation of feeding and energy expenditure. J Endocrinol. 2007 Apr;193(1):1-9. doi: 10.1677/JOE-06-0144. PMID: 17400797.
3. Bjørbaek C, Hollenberg AN. Leptin and melanocortin signaling in the hypothalamus. Vitam Horm. 2002;65:281-311. doi: 10.1016/s0083-6729(02)65068-x. PMID: 12481551.
4. Guo F, Bakal K, Minokoshi Y, Hollenberg AN. Leptin signaling targets the thyrotropin-releasing hormone gene promoter in vivo. Endocrinology. 2004 May;145(5):2221-7. doi: 10.1210/en.2003-1312. Epub 2004 Feb 5. PMID: 14764630.
5. York DA, Boghossian S, Park-York M. Melanocortin activity in the amygdala influences alcohol intake. Pharmacol Biochem Behav. 2011 Mar;98(1):112-9. doi: 10.1016/j.pbb.2010.12.010. Epub 2010 Dec 15. PMID: 21167196.
6. Wessells H, Fuciarelli K, Hansen J, Hadley ME, Hruby VJ, Dorr R, Levine N. Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: double-blind, placebo-controlled crossover study. J Urol. 1998 Aug;160(2):389-93. PMID: 9679884.
7. Lau JKY, Tian M, Shen Y, Lau SF, Fu WY, Fu AKY, Ip NY. Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer’s disease transgenic mouse model. Sci Rep. 2021 Feb 23;11(1):4359. doi: 10.1038/s41598-021-83932-4. PMID: 33623128; PMCID: PMC7902646.
8. Navarro M, Carvajal F, Lerma-Cabrera JM, Cubero I, Picker MJ, Thiele TE. Evidence that Melanocortin Receptor Agonist Melanotan-II Synergistically Augments the Ability of Naltrexone to Blunt Binge-Like Ethanol Intake in Male C57BL/6J Mice. Alcohol Clin Exp Res. 2015 Aug;39(8):1425-33. doi: 10.1111/acer.12774. Epub 2015 Jun 24. PMID: 26108334; PMCID: PMC4515169.
