Description
Cardarine (GW-501516) Powder — 2 Grams
Cardarine, also designated GW-501516, GW1516, or GSK-516, is a synthetic, non-steroidal agonist of peroxisome proliferator-activated receptor delta (PPARδ). Although it is often catalogued alongside SARMs, it is mechanistically distinct and does not bind the androgen receptor. This listing is a research-grade reference compound supplied in powder form for in vitro and laboratory investigation. Identity and purity are third-party verified and documented by a downloadable Certificate of Analysis.
- 99.87% purity (HPLC)
- Third-party verified
- 2,050 mg net
- Public COA
- UV-resistant foil pouch
Specifications & Documentation
- Compound
- Cardarine (GW-501516 / GW1516 / GSK-516)
- IUPAC Name
- 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]phenoxy]acetic acid
- CAS Number
- 317318-70-0
- Molecular Formula
- C₂₁H₁₈F₃NO₃S₂
- Molar Mass
- 453.50 g/mol
- Compound Class
- PPARδ agonist · Non-steroidal metabolic modulator
- WADA Classification
- Prohibited — Class S4 (Hormone and Metabolic Modulators)
- Form
- Crystalline powder
- Net Quantity
- 2,050 mg per pouch
- Verified Purity
- 99.87% by HPLC (current COA)
Third-Party Verification
Identity and purity are independently confirmed by MZ Biolabs (Tucson, AZ), a US DEA Schedule III licensed analytical facility (License RP0584676), using HPLC purity analysis and mass-spectrometry identity confirmation under Good Laboratory Practice (GLP) standards to support research reproducibility.
- Latest COA Date
- 07/03/2025
- Reported Purity
- 99.87%
- Methods
- HPLC–UV purity; MS identity confirmation
- Verifying Lab
- MZ Biolabs, Tucson, AZ (DEA Schedule III, RP0584676)
Current certificate of analysis for Cardarine (GW-501516), issued by MZ Biolabs. Tap to view full size.
Open or download the current Cardarine COA · View the full COA archive →
Storage & Handling
Store in a cool, dry place away from direct sunlight to maximize shelf life. Supplied in a UV-resistant foil pouch to minimize photodegradation.
- Packaging
- UV-resistant sealed foil pouch
- Storage
- Cool, dry, dark; away from direct sunlight
- Handling
- Standard laboratory PPE and analytical-grade equipment
- Intended Use
- Laboratory and in vitro research only
Quality & Analytical Transparency
Independent analysis has repeatedly found that research compounds sold online are frequently mislabeled or adulterated. A 2017 JAMA investigation that chemically analyzed products marketed as SARMs, a category that commonly includes GW-501516, found that only a minority accurately matched their labeled contents, and a substantial share contained unapproved or entirely different substances.[5] Third-party testing is the control that distinguishes a documented reference compound from an unverified one.
Research Context
GW-501516 emerged from a GlaxoSmithKline and Ligand Pharmaceuticals research program in the 1990s as a potent, selective PPARδ agonist. Early published work characterized its effects on cholesterol transport and lipid parameters in primate models[1] and on fatty acid β-oxidation in skeletal muscle in rodents,[2] and a small study in healthy volunteers examined lipid and lipoprotein endpoints.[3] Clinical development was discontinued in 2007 after long-term animal studies reported rapid development of cancers in multiple organs, a finding the World Anti-Doping Agency later highlighted in a formal health warning.[4] GW-501516 has since remained a research tool for studying PPARδ signaling and a target of anti-doping detection methods.
This material is supplied strictly as a reference compound to support such laboratory investigation. It is not a therapeutic product, dietary supplement, or sports supplement, and no clinical or performance outcomes are claimed or implied for any individual.
Compliance & Legal Status
Cardarine (GW-501516) is an investigational compound that has not been approved by the U.S. Food and Drug Administration for human use, and its clinical development was discontinued. It is not a dietary supplement, and marketing it for human ingestion is unlawful. It is supplied exclusively for laboratory research purposes.
Scientific References
- Oliver WR Jr, Shenk JL, Snaith MR, et al. A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport. Proc Natl Acad Sci USA. 2001;98(9):5306–5311.
- Tanaka T, Yamamoto J, Iwasaki S, et al. Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome. Proc Natl Acad Sci USA. 2003;100(26):15924–15929.
- Sprecher DL, Massien C, Pearce G, et al. Triglyceride:high-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor δ agonist. Arterioscler Thromb Vasc Biol. 2007;27(2):359–365.
- World Anti-Doping Agency. WADA issues alert on GW501516 [press release]. March 2013. WADA.org.
- Van Wagoner RM, Eichner A, Bhasin S, Deuster PA, Eichner D. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017;318(20):2004–2010.
- World Anti-Doping Agency. The Prohibited List, Section S4: Hormone and Metabolic Modulators. WADA.org.
Research Disclaimer
For laboratory research use only. This preparation is not approved by the FDA for human use. Cardarine / GW-501516 is not a dietary or sports supplement and is not intended for human or animal consumption.
All products on this website are intended exclusively for research and development purposes. The statements herein have not been evaluated by the U.S. Food and Drug Administration. Neither the statements nor the products are intended to diagnose, treat, cure, or prevent any disease. Sports Technology Labs are chemical suppliers, not medical practitioners; our expertise is sourcing and quality control.
Cardarine powder (GW-501516) research FAQs
How much Cardarine powder is supplied?
The current listing supplies approximately 2 g of Cardarine research powder, with a listed net quantity of 2,050 mg per pouch.
Where can researchers view the current Cardarine COA?
The current certificate of analysis is linked from the product page and the Sports Technology Labs COA library. The posted batch reports 99.87% purity by HPLC-UV-MS.
What is the difference between powder and liquid Cardarine?
Powder is supplied as raw research material and requires appropriate laboratory equipment and handling. Liquid Cardarine is available as a pre-formulated 20 mg/mL research solution in a 30 mL bottle.
How should Cardarine powder be stored and handled?
Keep the sealed pouch in a cool, dry place away from direct light and moisture. Use suitable laboratory controls and handling procedures. This material is for laboratory research only and is not for human or animal consumption.
What are the shipping and return terms?
In-stock orders are handled within one business day. After shipment, USPS delivery typically takes 2–5 business days. Returns are accepted within 60 days, and customers pay return shipping.





