Introductory Content

Understanding the SARMs Ban in 2021

SARMs are a class of nonsteroidal drugs that were initially developed for age- and disease-related muscle wasting. Researchers have investigated their potential for treating osteoporosis, Alzheimer’s disease, cancer, sexual dysfunction, multiple sclerosis, and muscle wasting. The research regarding the use of SARMs in humans is unfortunately limited, though. The science and athletic communities are well-aware […]

Where to Get SARMs: A Guide to Safe Online Purchasing

High-quality selective androgen receptor modulators (SARMs) are sought after in the research world for their potential to treat several vexing health conditions. These chemical compounds bind to androgen receptors with a degree of selectivity, which means they have a better safety margin than steroids and are believed to cause minimal adverse effects. SARMs for research […]

How to Buy SARMs Online Safely

There’s some buzz around Selective Androgen Receptor Modulators (SARMs) in the research world because of benefits found in early studies. They can be legally bought online for research purposes, but the process isn’t straightforward. The market for SARMs is largely unregulated, and hence, there’s always a risk of buying poor-quality adulterated products. A 2017 study published on JAMA Network showed that […]

What to Know Before You Buy SARMs

Selective Androgen Receptor Modulators (SARMs) have been the subject of some debate in the arena of performance enhancement science. Public perception has them confused with other compounds and products. It’s also true that not all labs treat SARMs with the gravity and transparency necessary to further positive research and promote a broader understanding of them […]

A List of SARMs and What Researchers Are Finding Out About Them

Selective Androgen Receptor Modulators (SARMs) have gotten a lot of attention in the last decade. Preliminary studies have revealed that specific SARMs and similar compounds — such as MK-677, Cardarine, RAD-140, and Ostarine — have benefits that warrant further investigation. Researchers are eager to unravel the full potential of this unique class of compounds. Here are […]

A Guide to SARMs and Their Legality

SARMs are known for building muscle, accelerating recovery from injuries, and enhancing performance, which has caused them to gain popularity in recent years. Those who are unfamiliar with these cutting-edge substances, may have some questions about how they work and whether they are safe and legal within the United States, however. This guide will help […]

What is RAD-140 (Testolone)?

RAD-140 is a SARM developed by Radius Health, Inc. for treatment of conditions like muscle wasting and breast cancer [1]. It exerts anabolic activity in muscle and connective tissue with little effect on the prostate and seminal vesicles. In addition, it may selectively compete and antagonize testosterone in these tissues. Scientists administered testosterone proprionate at […]

What is Andarine (S4)?

S4, also known as Andarine, was developed by GTX, inc for the treatment of muscle wasting, osteoporosis, and benign prostatic hypertrophy [1]. In a rat model, 1.6mg/kg bodyweight has been shown to significantly increase bone mineral density, lean mass and body composition. 3mg/kg/day demonstrated significant increases in muscle mass [1, 2]. In the ovariectomized rat […]

About LGD-4033

LGD-4033 is a 3rd generation non-steroidal oral SARM with a high affinity for the androgen receptor (Ki of ~1 nM). It is currently the second most popular SARM on the market. Unlike testosterone which exerts anabolic effects by the same pathway, LGD-4033 has high selectivity for receptors in skeletal muscle, bone, and connective tissue, with […]

What is GW501516 (aka Cardarine)? What You Need to Know

GW501516, also known as Cardarine, is not a SARM but rather a selective PPARδ and AMP-K modulator developed in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline for treatment of obesity, diabetes, dyslipidemia, cholesterol imbalance, and cardiovascular disease. PPARδ and AMP-K are the same pathways activated during exercise and are involved in energy production and fatty […]