TB-500 is a 43-amino-acid synthetic peptide analog of the active portion of thymosin Beta 4, a naturally occurring peptide in mammals produced by the thymus gland. TB-500 thymosin beta is a relatively small, long peptide with a molecular weight of almost 5 g/mol.
An examination of animal studies shows broad functionality of thymosin beta four or TB-500, including: wound healing, cardiac, nervous, and regeneration of damaged tendons and ligaments, improvement of neurological disease symptoms, and improvement in kidney and liver diseases. The TB-500 peptide is studied with a particular interest in the areas of spinal cord tissue repair, bone repair, muscle growth, ligament wound repair, and anti-aging medicine.
TB-500 vs. Other Peptides
Feature
TB-500
BPC-157
Thymosin Alpha-1
Source
Synthetic analog of TB-4
Gastric peptide fragment
Thymus-derived peptide
Key Mechanism of Action
Binds actin, promotes cell migration, proliferation, and differentiation
Modulates immune system function, gene expression, and hormone regulation
Boosts T-cell function
Immune Modulation from Studies
Moderate
Low
High
Research Model Focus
Heart, wounds, eyes
Ligaments, tendons, and gut
Immune disorders, infections
Model Synergies
✔️ Paired with BPC-157
✔️ Paired with TB-500
✔️ Paired with an immune stack
Why Buy TB-500 From Sports Technology Labs?
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At Sports Technology Labs, you can find the highest quality TB-500 thymosin beta 4 for sale anywhere on the internet.
When you buy peptides from Sports Technology Labs, you are choosing the highest quality products. Pure compounds are tested and certified by accredited American third-party labs that accept phone calls to verify the validity of their certificates. Our products are lyophilized in glass bottles and are stored in refrigeration to prevent degradation.
We run a transparent business, with no discreet payment methods necessary and no misrepresentation of our products, only the highest quality research chemicals available online, secured by our 60-day money-back guarantee. We offer free shipping on orders over $149, and if you need the products in a hurry, we offer express shipping as well. Customers who sign up for our email list get 10% off, and an additional 10% off for payment with cryptocurrency.
Sports Technology Labs is the best place to buy TB-500 peptide online because of our consistent, verifiable, high-quality products, safe bottling and packaging, fast shipping, and excellent customer service. And if you have any questions about our TB-500 Thymosin β4 and other products, you can also contact us, and we’ll respond as soon as possible.
Additional information
Weight
0.25 oz
Dimensions
2 × 1 × 1 in
TB-500
All Sports Technology Labs peptides are third-party tested by MZ Biolabs, an independent laboratory based in Arizona. While not bottled in the USA, every batch is tested here to verify accuracy and purity. Our Certificates of Analysis confirm that products meet the listed specifications.
In an animal model, mice that were given TB-500 showed much stronger healed fractures and blood vessels than the control group. The Mice treated with TB-500 thymosin Beta 4 had an increase in peak force to failure as well as improved connective tissue repair. After the mice were treated with TB-500 post-fracture, imaging showed substantial improvement in wound healing compared to subjects who did not receive TB-500, less scar tissue, and an increase in trabecular bone area.
This suggests that the TB-500 thymosin beta promoted the repair and regeneration of blood cells and connective tissue, as well as faster bone and muscle healing with fewer complications.
TB-500 Peptide and Kidney Health
Another study in mice suggested that low natural levels of Thymosin Beta 4 or TB-500 might accelerate the progression of known kidney disease. This correlation indicates that the body’s natural thymosin Beta 4, which is present in healthy individuals, appears to protect the kidney and may potentially help reduce the progression of kidney disease in animal cells. This may be due to the tendency of TB-500 to promote the growth of new blood vessels.
TB-500 and Nervous System Repair
TB-500’s effects on the spinal cord and traumatic brain injury have been studied in rats with potential applicability to repair and regenerate mammals. In one study, TB-500 was administered to rats after inducing spinal cord injury. The rats that received the TB-500 treatment showed significant improvements in their locomotor skills and behavior when compared to the control group of rats. The levels of inflammatory cytokines were reduced, the size of scars was markedly reduced, and levels of myelin proteins were increased above those in the control group.
TB-500 has also been shown to improve brain function after a traumatic brain injury (TBI). In rat studies, TB-500 has been shown to promote cell migration, form new blood vessel growth, create new brain cells, and establish new connections between existing brain cells.
TB-500 and Eye Health
A recent study observed the effects of TB-500 thymosin Beta 4 on subjects with diabetic retinopathy. After administering TB-500 eye drops to test subjects, researchers found that recovery time was significantly reduced following surgery. Corneas from test subjects affected by diabetic retinopathy contained less thymosin Beta 4 or TB-500 than healthy corneas. In addition to this main group of test subjects, those suffering from chronic dry eye were given thymosin Beta 4 synthetic version TB-500 eye drops and noted an improvement in symptoms, with very few complications.
Anti-Inflammatory and Cellular Repair
TB-500 thymosin Beta 4 showed acceleration in recovery from burns, diabetic ulcers, pressure ulcers, stasis ulcers, and epidermolysis wounds in subjects. TB-500 thymosin Beta 4 is known to promote muscle cell growth and mitochondrial RNA replication. TB-500 thymosin beta promotes cell building protein and reduces inflammation and has been shown to help regenerate muscle fibers and address inflammation in the injured location, providing accelerated muscle regeneration.
Known mechanisms for this effect include, but are not limited to, improvement in blood cell and blood vessel formation, anti-inflammatory activity, and increased platelet aggregation at wound sites.
Mechanism of Action: How TB-500 Works
TB-500, a synthetic version of Thymosin Beta-4 (TB-4), promotes healing by binding to actin, a protein crucial for cell movement and structure. This interaction facilitates cell migration, proliferation, and differentiation, making it particularly effective in tissue repair and angiogenesis (formation of new blood vessels). (Source)
TB-500’s low molecular weight allows it to travel long distances through tissues, targeting areas of injury more efficiently than many other peptides. It is often used in research exploring myocardial (heart) repair, wound healing, and inflammation control.
This preparation is for in vitro laboratory research purposes only by licensed professionals and is not approved by the FDA for bodily introduction of any kind into humans or animals. TB-500 is not a drug, food, supplement, or cosmetic and may not be misbranded, misused, or mislabeled as a drug, food, supplement, or cosmetic.
1. Is TB-500 the same as Thymosin Beta-4?
TB-500 is a synthetic peptide that mimics the effects of the natural protein Thymosin Beta-4. It is often referred to as a research analog.
2. What is the typical research amount for TB-500?
Quantities vary, but studies typically test between 2 mg and 10 mg per week, depending on the animal model and application. (Source)
3. How should TB-500 be stored?
Store lyophilized TB-500 at room temperature, away from light and moisture. Reconstituted solutions should be refrigerated and used within a few weeks.
4. Can TB-500 be combined with other peptides?
Yes, researchers often combine TB-500 with BPC-157 for synergistic effects in wound healing and inflammation studies.
5. What is TB-500 used for?
TB-500 is a peptide that is being researched for its regenerative effects in a variety of tissues, including muscle, connective tissue, and bone. It is also the subject of studies on a variety of inflammatory, cardiovascular, and neurological conditions.
6. Is TB-500 peptide better than BPC-157?
TB-500 has demonstrated greater efficacy in the regeneration of peripheral tissues, including muscle and connective tissue, while BPC-157 is considered more effective in the healing of the gastrointestinal tract.
7. What is the difference between TB-500 and BPC-157?
TB-500 is a synthetic analogue of Thymosin Beta, a healing peptide that is naturally secreted by the thymus gland. BPC-157 is a modified section of Body Protection Compound, a healing peptide naturally produced in the stomach.
Scientific References:
1. Tokura Y, Nakayama Y, Fukada S, Nara N, Yamamoto H, Matsuda R, Hara T. Muscle injury-induced thymosin β4 acts as a chemoattractant for myoblasts. J Biochem. 2011 Jan;149(1):43-8. doi: 10.1093/jb/mvq115. Epub 2010 Sep 29. PMID: 20880960.
3. Vasilopoulou E, Kolatsi-Joannou M, Lindenmeyer MT, White KE, Robson MG, Cohen CD, Sebire NJ, Riley PR, Winyard PJ, Long DA. Loss of endogenous thymosin β4 accelerates glomerular disease. Kidney Int. 2016 Nov;90(5):1056-1070. doi: 10.1016/j.kint.2016.06.032. Epub 2016 Aug 26. PMID: 27575556; PMCID: PMC5073078.
4. Kleinman HK, Sosne G. Thymosin β4 Promotes Dermal Healing. Vitam Horm. 2016;102:251-75. doi: 10.1016/bs.vh.2016.04.005. Epub 2016 May 24. PMID: 27450738.
5. Goldstein AL, Kleinman HK. Advances in the basic and clinical applications of thymosin β4. Expert Opin Biol Ther. 2015;15 Suppl 1:S139-45. doi: 10.1517/14712598.2015.1011617. Epub 2015 Jun 22. PMID: 26096726.
7. Cheng P, Kuang F, Zhang H, Ju G, Wang J. Beneficial effects of thymosin β4 on spinal cord injury in the rat. Neuropharmacology. 2014 Oct;85:408-16. doi: 10.1016/j.neuropharm.2014.06.004. Epub 2014 Jun 14. PMID: 24937047.
8. Xiong Y, Mahmood A, Meng Y, Zhang Y, Zhang ZG, Morris DC, Chopp M. Neuroprotective and neurorestorative effects of thymosin β4 treatment following experimental traumatic brain injury. Ann N Y Acad Sci. 2012 Oct;1270:51-8. Doi: 10.1111/j.1749-6632.2012.06683.x. PMID: 23050817; PMCID: PMC3547647.
