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Epitalon 10mg



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What is Epitalon?

Epitalon, also known as Epithalon, is a short, four amino acid synthetic polypeptide derivative of epithalamin that activates the natural production of telomerase enzyme and stimulates melatonin release from the human pineal gland.

Epithalamin peptide in vivo contributes to the regulation of the cell replication and the anterior pituitary gland. Epitalon was discovered by Russian doctor and peptide engineer Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology and has been studied for over 35 years.

Epitalon is coveted by many anti aging experts and regarded as a potential fountain of youth. Research in mice and rats has shown that Epitalon can improve age related diseases, skin health and appearance, increase resistance to emotional stress, stimulate the production of new cells and rejuvenate muscle cells, and increase lifespan by delaying age-related changes in reproductive and immune systems.

This effect may be greater in individuals who do not have naturally longer telomeres. Preliminary studies have displayed significant effects of Epitalon treatment on certain types of cancerous cells, infections, and DNA regulation.

Epitalon and DNA Protection

Epitalon peptide is shown to exhibit antioxidant activity in the body by aiding in the elimination of free radicals. Evidence from experiments on somatic cells shows that Epitalon protein treatment activates an enzyme called telomerase and stimulates the natural production of telomerase.

 Telomere shortening correlates with aging and Telomerase is one of several naturally occurring components that are considered the potential fountain of youth because it may stimulate the production of new cells and rejuvenate old ones. 

Telomerase enzyme activation leads directly to an improvement in cell health, longer telomeres, a decrease in errors contained in a strand of DNA, and protection of chromosomes and DNA from damage.

Research also shows that Epitalon interacts directly with DNA to enhance the expression of certain genes specifically regulating the CD5, IL-2, MMP2, and Tram1 genes, and the natural production of telomerase.

Anti-tumor Effects of Epithalon

In rats, Epitalon was able to improve muscle cell health and decrease tumor growth. Synthetic Epitalon Peptide treatment reduced tumor growth, and also prevented metastasis (the spread of cancer). As a result, epithalon peptide is currently under investigation as a potential treatment for Her-2/neu positive breast cancers, leukemia, and testicular cancer.

Epitalon and Sleep Quality

Studies on rats have demonstrated that Epitalon and related peptides impact circadian rhythm through both the creation and discharge of melatonin by affecting two proteins, pCREB transcription protein and arylalkylamine-N-acetyltransferase (AANAT). 

These two genes contribute to regular production of melatonin and in the day/night release of melatonin from the pineal gland. Studies done with monkeys suggest that Epitalon peptide therapy brings melatonin release back to normal.

Improvements in circadian regularity and deeper sleep have been known to improve skin health and appearance, stimulate production of new muscle cells, regulate the anterior pituitary gland, increase cell replication, promote resistance to emotional stress and age related diseases. 

Deep, restorative sleep is regarded by many health experts as the natural fountain of youth and critical to muscle cell health, the production of new cells, and life extension.

Epitalon Side Effects

Aside from potential injection site inflammation, Epitalone therapy has yet to show significant side effects in human and animal studies however this does not mean that the use of Epitalon peptide is safe. Long term clinical trials are needed to confirm the safety, side effects, clinical significance, and relative efficacy of Epithalon therapy.

Data on our Epitalon for sale

CAS Number: 307297-40-1

Formula: C14H22N4O9

Sequence: Ala-Glu-Asp-Gly

Molar Mass: 390.35 g/mol

Class: Tetrapeptide

Storage: Keep refrigerated upon reconstitution.

  • Lyophilized sample in sterile glass vial.
  • Minimum 99.8% pure.
  • 10mg Epitalon per vial.
  • Diluent and laboratory supplies not included.

This preparation is for in vitro laboratory research purposes only by licensed professionals and is not approved by the FDA for bodily introduction of any kind into humans or animals. Epitalon / Epithalon is not a drug, food, supplement, or cosmetic and may not be misbranded, misused, or mislabeled as a drug, food, supplement, or cosmetic. 

Epitalon FAQs

The primary role of Epitalon is to increase the production of telomerase, a natural enzyme that protects and restores telomeres, promoting the replication of DNA and the production of new cells.

Epitalon works with the pineal gland in the brain to form new cells and may increase muscle mass and bone density.

Epitalon was found to restore reproductive function in older rats by restoring the female estrus cycle and increasing plasma testosterone levels by 30% in males.

Why buy Epitalon 10mg from Sports Technology Labs?

Buy Epitalon

If you want to buy Epithalon, it’s not hard to find a seller, but Sports Technology Labs is the best place to buy Epitalon online because of their consistent, verifiable high quality, fast shipping, and great customer service.

A quick search will uncover plenty websites offering Epitalon for sale. Not all of these companies are trustworthy and in many cases, you can’t be certain what you are getting when you buy peptides from them, especially if they do not have third party certificates. 

At Sports Technology Labs you can buy the highest quality Epitalon with confidence because every batch is third party tested and certified by an accredited US-based laboratory. When you buy peptides from Sports Technology Labs you are choosing the highest quality products. Our products come lyophilized in glass bottles and are stored in refrigeration to prevent degradation in storage. 

We run a transparent business, with no discreet payment methods necessary and no misrepresentation of our products, only the highest quality research chemicals available online, secured by our 60-day money-back guarantee. 

We provide free shipping for orders exceeding $149, and for those who require expedited delivery, we also offer express shipping. Customers who subscribe to our email list enjoy a 10% discount, and an extra 10% off when paying with cryptocurrency. If you have any questions about our Epitalon for sale for laboratory research use, please don’t hesitate to contact us.

Scientific References:

1. Khavinson VKh, Bondarev IE, Butyugov AA. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bull Exp Biol Med. 2003 Jun;135(6):590-2. doi: 10.1023/a:1025493705728. PMID: 12937682.

2. Dzhokhadze TA, Buadze TZh, Gaĭozishvili MN, Rogava MA, Lazhava TA. [Functional regulation of genome with peptide bioregulators by hypertrophic cardiomyopathy (by patients and relatives)]. Georgian Med News. 2013 Dec;(225):94-7. Russian. PMID: 24423684.

3. Anisimov VN, Khavinson VKh, Popovich IG, Zabezhinski MA, Alimova IN, Rosenfeld SV, Zavarzina NY, Semenchenko AV, Yashin AI. Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. Biogerontology. 2003;4(4):193-202. doi: 10.1023/a:1025114230714. PMID: 14501183.

4. Khavinson VKh, Tarnovskaya SI, Linkova NS, Pronyaeva VE, Shataeva LK, Yakutseni PP. Short cell-penetrating peptides: a model of interactions with gene promoter sites. Bull Exp Biol Med. 2013 Jan;154(3):403-10. doi: 10.1007/s10517-013-1961-3. PMID: 23484211.

5. Vinogradova IA, Bukalev AV, Zabezhinski MA, Semenchenko AV, Khavinson VKh, Anisimov VN. Effect of Ala-Glu-Asp-Gly peptide on life span and development of spontaneous tumors in female rats exposed to different illumination regimes. Bull Exp Biol Med. 2007 Dec;144(6):825-30. doi: 10.1007/s10517-007-0441-z. PMID: 18856211.

6. Kossoy G, Anisimov VN, Ben-Hur H, Kossoy N, Zusman I. Effect of the synthetic pineal peptide epitalon on spontaneous carcinogenesis in female C3H/He mice. In Vivo. 2006 Mar-Apr;20(2):253-7. PMID: 16634527.

7. Anisimov VN, Khavinson VK, Provinciali M, Alimova IN, Baturin DA, Popovich IG, Zabezhinski MA, Imyanitov EN, Mancini R, Franceschi C. Inhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in HER-2/neu transgenic mice. Int J Cancer. 2002 Sep 1;101(1):7-10. doi: 10.1002/ijc.10570. PMID: 12209581.

8. Anisimov VN, Khavinson VKh, Alimova IN, Semchenko AV, Yashin AI. Epithalon decelerates aging and suppresses development of breast adenocarcinomas in transgenic her-2/neu mice. Bull Exp Biol Med. 2002 Aug;134(2):187-90. doi: 10.1023/a:1021104819170. PMID: 12459848.

9. Vinogradova IA, Bukalev AV, Zabezhinski MA, Semenchenko AV, Khavinson VKh, Anisimov VN. Geroprotective effect of ala-glu-asp-gly peptide in male rats exposed to different illumination regimens. Bull Exp Biol Med. 2008 Apr;145(4):472-7. doi: 10.1007/s10517-008-0121-7. PMID: 19110597.

10. Khavinson VKh, Shataeva LK, Chernova AA. Effect of regulatory peptides on gene transcription. Bull Exp Biol Med. 2003 Sep;136(3):288-90. doi: 10.1023/ PMID: 14666197.

11. Korkushko OV, Lapin BA, Goncharova ND, Khavinson VKh, Shatilo VB, Vengerin AA, Antoniuk-Shcheglova IA, Magdich LV. [Normalizing effect of the pineal gland peptides on the daily melatonin rhythm in old monkeys and elderly people]. Adv Gerontol. 2007;20(1):74-85. Russian. PMID: 17969590.

12. Yue X, Liu SL, Guo JN, Meng TG, Zhang XR, Li HX, Song CY, Wang ZB, Schatten H, Sun QY, Guo XP. Epitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitro. Aging (Albany NY). 2022 Apr 12;14(7):3191-3202. doi: 10.18632/aging.204007. Epub 2022 Apr 12. PMID: 35413689; PMCID: PMC9037278.

13. Epitalon Peptide: Exploring its Potential for Anti-Aging and Longevity. Peptide Information (2023).