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What is KPV Peptide?
KPV peptide (Lysine-Proline-Valine) is a tripeptide known for its powerful anti-inflammatory properties. This peptide is naturally derived from the alpha-melanocyte-stimulating hormone (α-MSH) and has been extensively studied for its potential therapeutic applications in treating various inflammatory diseases, including those affecting the gastrointestinal tract and skin.
KPV Peptide and Ulcerative Colitis
Recent studies have demonstrated the effectiveness of KPV peptide in managing ulcerative colitis, a chronic inflammatory bowel disease (IBD). Research conducted by Xiao et al. explored the orally targeted delivery of KPV using hyaluronic acid-functionalized nanoparticles. The study showed that KPV, when delivered via this method, significantly alleviated symptoms of ulcerative colitis in animal models. These findings suggest that KPV peptide could offer a novel therapeutic strategy for reducing inflammation in the gastrointestinal tract and promoting healing in patients suffering from ulcerative colitis.
KPV Peptide and Skin Health
KPV peptide has also shown promise in transdermal applications, particularly for skin health and inflammation. A study on the transdermal iontophoretic delivery of KPV demonstrated the peptide’s ability to efficiently cross microporated human skin. This delivery method could enable KPV peptide to be used in topical treatments for skin conditions that involve inflammation, such as psoriasis or eczema. The ability to deliver KPV through the skin broadens its potential applications in dermatology, providing a non-invasive option for managing inflammation-related skin disorders.
KPV Peptide and Anti-Inflammatory Mechanisms
The anti-inflammatory action of KPV peptide extends beyond localized effects, as it has been found to inhibit systemic inflammation. In research focusing on human bronchial epithelial cells, KPV peptide and other melanocortin-related peptides have demonstrated the ability to suppress inflammation. The mechanism of KPV action is related to its interaction with the melanocortin receptor 3 (MC3R). This interaction plays a critical role in mitigating inflammation in both cellular and systemic contexts, positioning KPV peptide as a promising therapeutic option for conditions marked by excessive inflammatory responses.
Data on our KPV for sale
CAS Number: 67727-97-3
Formula: C16H30N4O4
Sequence: Lys-Pro-Val
Molar Mass: 342.43 g/mol
Half life: 4 hours
Class: Alpha-MSH, ACTH, MSH
Storage: Keep refrigerated upon reconstitution.
- Lyophilized sample in sterile glass vial.
- Minimum 98% pure.
- 5mg KPV per vial.
- Diluent and laboratory supplies not included.
KPV 5mg is intended solely for in vitro laboratory research conducted by licensed professionals. This compound is not approved by the FDA for any form of administration to humans or animals. It is neither a drug, food, dietary supplement, nor a cosmetic product. It is crucial to avoid any misbranding, misuse, or mislabeling of KPV as any of these categories.
Ensure that KPV 5mg is used strictly in accordance with research guidelines and regulatory standards.
How does KPV Peptide work?
KPV peptide works by interacting with melanocortin receptors to suppress inflammation at both the cellular and systemic levels. It has been shown to reduce inflammatory markers in various disease models, including ulcerative colitis and skin inflammation.
Can KPV Peptide be used for skin conditions?
Yes, KPV peptide has been effectively delivered transdermally in research settings, showing promise in treating inflammatory skin conditions like psoriasis and eczema, but more research must take place to validate these findings.
What are the potential uses of KPV Peptide in research and laboratory settings?
KPV peptide is being studied for its effects on gastrointestinal diseases like ulcerative colitis, skin disorders involving inflammation, and even respiratory inflammation through its action on bronchial epithelial cells.
Why Buy KPV Peptide from Sports Technology Labs?
At Sports Technology Labs, we offer the highest-quality KPV peptide for sale online. Our peptides are tested for purity and formulated for research use only. Whether you are investigating the anti-inflammatory properties of KPV or exploring its other research potentials, our product ensures the integrity and reliability needed for your research. When you buy peptides from Sports Technology Labs you are choosing the highest quality products.
Premium KPV Peptides: Pure, Verified, and Quality Assured
Discover the finest KPV peptides, rigorously tested and certified by renowned American third-party labs. Our lab partners are fully accredited and accessible by phone, ensuring the authenticity and validity of their certifications.
Why Choose Us?
- Top-Quality Peptides: Our KPV peptides are lyophilized and sealed in glass vials, with refrigeration storage to maintain their potency and prevent degradation.
- Transparent Business Practices: We pride ourselves on honesty and integrity. No discreet payment methods are needed, and we guarantee clear product representation with our top-tier research chemicals.
- Money-Back Guarantee: We stand by our products with a 60-day money-back guarantee, ensuring your complete satisfaction.
- Free Shipping: Enjoy free shipping on orders over $149. For urgent needs, we offer express shipping options.
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Why Sports Technology Labs?
When it comes to purchasing KPV peptides online, Sports Technology Labs stands out for our commitment to quality. Our consistent, high-grade products are securely bottled and packaged, with prompt shipping and exceptional customer service. Have questions? Reach out to us, and we’ll provide a swift and helpful response at [email protected].
Scientific References:
1. Getting, S. J., Schiöth, H. B., & Perretti, M. (2003). Dissection of the anti-inflammatory effect of the core and C-terminal (KPV) α-melanocyte-stimulating hormone peptides. Journal of Pharmacology and Experimental Therapeutics, 306(2), 631-637.
2. Land, S. C. (2012). Inhibition of cellular and systemic inflammation cues in human bronchial epithelial cells by melanocortin-related peptides: mechanism of KPV action and a role for MC3R agonists. International journal of physiology, pathophysiology and pharmacology, 4(2), 59.
3. Pawar, K., Kolli, C. S., Rangari, V. K., & Babu, R. J. (2017). Transdermal iontophoretic delivery of lysine-proline-valine (KPV) peptide across microporated human skin. Journal of pharmaceutical sciences, 106(7), 1814-1820.
4. Xiao, B., Xu, Z., Viennois, E., Zhang, Y., Zhang, Z., Zhang, M., … & Merlin, D. (2017). Orally targeted delivery of tripeptide KPV via hyaluronic acid-functionalized nanoparticles efficiently alleviates ulcerative colitis. Molecular Therapy, 25(7), 1628-1640.
