Description
Ipamorelin Overview
Ipamorelin is a pentapeptide composed of a concise sequence of amino acids: Aib-His-D-2-Nal-D-Phe-Lys-NH2. This peptide is known for its ability to stimulate the pituitary gland to release growth hormone. It is also known for its positive impact on promoting lean muscle mass and facilitating weight loss. Moreover, it produces less effects on the:
- thyroid-stimulating hormone
- luteinizing hormone
- prolactin
- follicle-stimulating hormone
- ACTH
- cortisol release
Ipamorelin falls into the category of Growth Hormone-Releasing Peptides (GHRP), acknowledged for their ability to elevate growth hormone levels and offer a wide array of clinical advantages. These include:
- The management of body fat and weight
- The enhancement of skin elasticity and function
- The reduction in cortisol production
- The enhancements in energy levels and sleep quality
Ipamorelin is frequently likened to GHRP 6 and GHRP 2 due to their shared similarities in mechanism, action, and functionality.
Benefits Under Investigation With Ipamorelin
Side Effects from Glucocorticoids
Ipamorelin has shown potential in reducing or reversing the side effects of glucocorticoid use. The side effects from long term glucocorticoid use can lead to inflammatory conditions such as cancer and autoimmune diseases. As well, they are known to decrease lean muscle tissue and intramuscular amino acids while increasing body fat. The pituitary gland stimulation Ipamorelin causes may help decrease these effects.
Muscle Wasting
Glucocorticoids can cause an unwanted side effect; muscle wasting. In recent studies on rats, glucocorticoid treatment was administered. As a result of the study, the rats had a decreased amount of amino acid wasting. This was seen in the liver and there were also improved nitrogen balance levels in muscles.
Bone Loss Protection
When taking glucocorticoids for a long period of time, diminished bone density can result, leading to the heightened susceptibility to fractures. Clinical investigations have shown the potential of Ipamorelin to counteract the bone loss associated with these corticosteroids. It does this by influencing the pituitary gland. This beneficial effect seen by this process was observed in experiments involving rats. The peptide actively stimulated the process of bone formation during this clinical study. Furthermore, Ipamorelin has demonstrated the capability to help bone mineral density by reinforcing the structural integrity of both pre-existing and newly formed bones.
Potential Benefits for Diabetes
Research conducted on diabetic rats suggests that ipamorelin administration may stimulate insulin release by binding to the calcium channel found on pancreatic cells. These effects on the pancreas could potentially aid in the development of preventative measures for type 2 diabetes.
Diagnostic Applications in Cancer and Heart Failure
Ipamorelin, a peptide known for its interaction with the ghrelin receptor, demonstrates an increased affinity in specific scenarios, particularly in certain cancer types and instances of heart failure. Ongoing research endeavors are focused on exploring the prospective utility of Ipamorelin as a positron emission tomography (PET) probe, aimed at enhancing the diagnostic capabilities for these medical conditions. Preliminary in vitro investigations have yielded compelling evidence in favor of this notion, substantiating the potential efficacy of Ipamorelin as a PET probe.
Ipamorelin and Post-operative Ileus
Post-operative ileus (POI) is a condition characterized by the temporary paralysis of the gastrointestinal system, resulting in the inability to ingest nutrients through eating. This condition is common after specific types of surgery, particularly abdominal surgery. Ipamorelin has been investigated for its potential to shorten the clinical recovery time and improve the ability to eat in individuals affected by POI.
Data on our Ipamorelin for sale
CAS Number: 170851-70-4
Formula: C38H49N9O5
Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
Molar Mass: 711.85 g/mol
Half life: 2 hours
Class: Peptide
Storage: Keep refrigerated upon reconstitution.
- Lyophilized sample in sterile glass vial.
- Minimum 99% pure.
- 5mg Ipamorelin per vial.
- Diluent and laboratory supplies not included.
This preparation is for in vitro laboratory research purposes only by licensed professionals and is not approved by the FDA for bodily introduction of any kind into humans or animals. Ipamorelin is not a drug, food, supplement, or cosmetic and may not be misbranded, misused, or mislabeled as a drug, food, supplement or cosmetic.
Ipamorelin FAQs
Little effect on thyroid-stimulating hormone, luteinizing hormone, prolactin, follicle-stimulating hormone, ACTH, or cortisol release
Comparable to GHRP 6 peptide and GHRP 2 in action
Reduces/reverses side effects of glucocorticoid use
Decreases muscle wasting and improves nitrogen balance
Slows or stops bone loss, increases bone formation and mineral density
Stimulates insulin release, potential for preventing type 2 diabetes
Possible use in PET for cancer and heart failure diagnosis
Shortens clinical recovery time and improves eating ability in POI
After reconstitution, store in the refrigerator
Refrigeration temperature: 10.25 degrees Celsius or 50.7 degrees Fahrenheit
Why buy Ipamorelin from Sports Technology Labs?
If you are trying to figure out where to buy Ipamorelin peptide, there are many options out there. To buy Ipamorelin from a randomly selected company is dangerous. Most companies with peptides for sale do not test their products, or hide their certificates or contact information for their third party labs from customers. What can they be hiding?
At Sports Technology Labs you can find the highest quality Ipamorelin for sale anywhere on the internet. When you buy peptides from Sports Technology Labs you are choosing the highest quality products.
Pure compounds tested and certified by accredited American third party labs that accept phone calls to verify the validity of their certificates. Our products come lyophilized in glass bottles and are stored in refrigeration to prevent degradation in storage. We run a transparent business, with no discreet payment methods necessary and no misrepresentation of our products, only the highest quality research chemicals available online, secured by our 60-day money-back guarantee.
Sports Technology Labs is the best place to buy Ipamorelin online because of our consistent, verifiable high quality products, safe bottling and packaging, fast shipping, and great customer service. We provide free shipping for orders exceeding $149, and for those who require expedited delivery, we also offer express shipping. Customers who subscribe to our email list enjoy a 10% discount, and an extra 10% off when paying with cryptocurrency. And if you have any questions about our Ipamorelin for sale for laboratory research use, please don’t hesitate to contact us.
Scientific References:
1. Raun K, Hansen BS, Johansen NL, Thøgersen H, Madsen K, Ankersen M, Andersen PH. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998 Nov;139(5):552-61. doi: 10.1530/eje.0.1390552. PMID: 9849822.
2. Aagaard NK, Grøfte T, Greisen J, Malmlöf K, Johansen PB, Grønbaek H, Ørskov H, Tygstrup N, Vilstrup H. Growth hormone and growth hormone secretagogue effects on nitrogen balance and urea synthesis in steroid treated rats. Growth Horm IGF Res. 2009 Oct;19(5):426-31. doi: 10.1016/j.ghir.2009.01.001. Epub 2009 Feb 23. PMID: 19231263.
3. Andersen NB, Malmlöf K, Johansen PB, Andreassen TT, Ørtoft G, Oxlund H. The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation of adult rats. Growth Horm IGF Res. 2001 Oct;11(5):266-72. doi: 10.1054/ghir.2001.0239. PMID: 11735244.
4. Svensson J, Lall S, Dickson SL, Bengtsson BA, Rømer J, Ahnfelt-Rønne I, Ohlsson C, Jansson JO. The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats. J Endocrinol. 2000 Jun;165(3):569-77. doi: 10.1677/joe.0.1650569. PMID: 10828840.
5. Adeghate E, Ponery AS. Mechanism of ipamorelin-evoked insulin release from the pancreas of normal and diabetic rats. Neuro Endocrinol Lett. 2004 Dec;25(6):403-6. PMID: 15665799.
6. Fowkes MM, Lalonde T, Yu L, Dhanvantari S, Kovacs MS, Luyt LG. Peptidomimetic growth hormone secretagogue derivatives for positron emission tomography imaging of the ghrelin receptor. Eur J Med Chem. 2018 Sep 5;157:1500-1511. doi: 10.1016/j.ejmech.2018.08.062. Epub 2018 Aug 23. PMID: 30282322.
7. Beck DE, Sweeney WB, McCarter MD; Ipamorelin 201 Study Group. Prospective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients. Int J Colorectal Dis. 2014 Dec;29(12):1527-34. doi: 10.1007/s00384-014-2030-8. Epub 2014 Oct 21. PMID: 25331030.
8. Greenwood-Van Meerveld B, Tyler K, Mohammadi E, Pietra C. Efficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileus. J Exp Pharmacol. 2012 Oct 19;4:149-55. doi: 10.2147/JEP.S35396. PMID: 27186127; PMCID: PMC4863553.
9. Ipamorelin Peptide: Exploring its Potential in Growth Hormone Stimulation and Health. Peptide Information (2023).
