The most widely researched SARM: MK-2866 (Ostarine)

MK-2866, also known as Ostarine is the most researched and most widely sought after SARM by scientists available. It was developed and researched as a potential aid to prevent cancer-related muscle wasting.

Buy MK-2866 (Ostarine)

MK-2866 (Ostarine) and Muscle

Ostarine binds selectively to androgen receptors in muscle, connective tissue, and bone while avoiding receptors in the hair and prostate. Androgen receptors are programmed to receive information about steroidal hormones like testosterone and DHT.

By stimulating these receptors, Ostarine mimics the action of exogenous testosterone on muscles without the visible androgenic side effects of testosterone like hair loss or prostate growth. By 2007, Ostarine was in a Phase II clinical trial.

Testing

In 2011 a double-blind, placebo-controlled phase II trial focusing on older male subjects and postmenopausal female subjects showed statistically significant improvements in lean body mass, connective tissue health, and physical function with no significant adverse effects typical to steroids.

Subjects also did not display the type of bloating and edema that is common with growth hormone or growth-hormone producing products.

Research In Rats

In a recent study, researchers sought to investigate the effects of ostarine on bone healing in ovariectomized rats. They utilized Sprague-Dawley rats that were either ovariectomized (Ovx, n=46) or left intact (Non-Ovx, n=10) at 3 months of age.

After an 8 weeks period, they created an osteotomy of the tibia metaphysis in all rats, and the Ovx rats were divided into four groups: untreated Ovx (n=10) and three Ovx groups (each of 12 rats) treated with ostarine They analyzed bone healing after a period of five weeks.

The findings revealed that the OS-4 dose significantly enhanced callus formation, increased callus density, accelerated bridging time of the osteotomy, and elevated alkaline phosphatase gene expression in callus and its protein expression in serum. 

In contrast, most of the callus parameters were diminished in the Ovx group. All OS showed a significant increase in the weight of the gastrocnemius muscle, while only partially enhancing uterus weight in OS-0.4 and OS-4. Serum cholesterol levels were reduced, and serum phosphorus was elevated in OS-0.04 and OS-4.

Overall, the results suggest that ostarine has a positive effect on early bone healing in ovariectomized rats. Given its favorable effects on non-osteotomized bone and muscle, the study suggests ostarine could be further explored as a therapy for osteoporosis. 

It is to note that this study did not test the effects of body fat (regarding reduce body fat or increase body fat), muscle mass (regarding muscle loss, muscle wastage, or build muscle), insulin resistance, or heart health. Further testing on mice must occur on a selective basis to gain insight in these areas of study.

What Benefits of MK2866 are Researchers Studying and Why?

1. The effect on lean body mass without androgenic or estrogenic side effects or edema.

2. Most widely studied SARM.

3. The effect on healing of muscle, bone, and connective tissue.

4. The risk of virilization in female subjects.

AT THIS TIME, OSTARINE / MK2866 IS ONLY APPROVED FOR LABORATORY RESEARCH AND IS NOT SOLD FOR HUMAN CONSUMPTION.

Where to buy Ostarine

Hundreds of online sources claim to sell legit Ostarine. Many of these companies do not vet their raw materials. 

Sports Technology Labs sells the highest quality SARMs guaranteed through strict quality control standards and every batch of our MK 2866 is third-party tested by an American laboratory for minimum 98% purity, the standard used by Universities and Chemical Suppliers around the world. 

We carry pure Ostarine powder as well as a convenient Liquid Ostarine solution.

If you are looking for good customer service, or even better, great customer service, look no further than Sports Technology Labs. We place you as a researcher first and will answer most emails within 24 hours time. 

If you are a repeat customer, please make sure you subscribe to our email list as we keep up to date on new products and articles of further research monthly. Have a suggestion for what you are trying to obtain for your research use? 

Send us an inquiry as we guarantee we will be the best place to buy ostarine that comes in 25mg ml bottles. We are the best place to buy other sarms and research chemicals for your rat model and clinical studies as well, so please feel free to reach out at [email protected].

Abuse Warning

Ostarine Mk 2866 is an investigational compound still awaiting FDA approval and is not dietary supplements. At Sports Technology Labs we are chemical suppliers, not medical doctors, and our expertise is sourcing and quality control. 

Sports Technology Labs does not encourage or condone consumer use of SARMs products, they are for research purposes only. Anecdotal reports and guides may not match those used in carefully designed medical research protocols and may pose a serious risk of adverse effects in users. 

Individual variables, comorbidities, and polypharmacy can also contribute significantly to the risk of health problems.

Scientific References:

1. Zhang, Xuqing; Lanter, James C; Sui, Zhihua (8 June 2009). “Recent advances in the development of selective androgen receptor modulators”. Expert Opinion on Therapeutic Patents. 19 (9): 1239–1258. doi:10.1517/13543770902994397. PMID 19505196. The first quoted sentence is cited to Published PCT application WO2008127717

2. Nagle, Mike (7 November 2007). “Merck flexes muscle with GTx deal”. Outsourcing Pharma.

3. Dalton, James T.; Barnette, Kester G.; Bohl, Casey E.; Hancock, Michael L.; Rodriguez, Domingo; Dodson, Shontelle T.; Morton, Ronald A.; Steiner, Mitchell S. (September 2011). “The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial”. Journal of Cachexia, Sarcopenia and Muscle. 2 (3): 153–161. doi:10.1007/s13539-011-0034-6. PMC 3177038. PMID 22031847.

4. http://www.vacansoleildcm.co.uk/nieuws/nikita-novikov-provisionally-suspended-after-possible-breach-of-anti-doping-rules.html

5. http://www.dpa-international.com/news/sports2/azerbaijans-beji-fails-doping-test-at-european-games-a-45758559.html

6. http://espn.go.com/boxing/story/_/id/15751796/lucian-bute-tested-positive-draw-vs-badou-jack

7. Russian boxer Povetkin tests positive, fight with Canadian Stiverne cancelled – WBC”. RT International. Retrieved 2016-12-17.

8. https://triathlonmagazine.ca/feature/two-american-pro-triathletes-reveal-doping-violations-today/

9. https://mmajunkie.com/2017/02/tom-lawlor-gets-2-year-suspension-from-usada-for-ostarine

10. https://mmajunkie.com/2016/02/tim-means-pulled-from-ufc-fight-night-83-headliner-after-failed-usada-test

11. “Oakland A’s starter Frankie Montas hit with 80-game PED suspension”. USA Today. June 21, 2019. Retrieved June 21, 2019.

12. Bieler, Des (25 July 2019). “Failed PED test has a highly paid offensive lineman sharing polygraph results”. Washington Post. Retrieved 25 July 2019.

13. https://mmajunkie.com/2016/02/tim-means-pulled-from-ufc-fight-night-83-headliner-after-failed-usada-test