Insulin-like Growth Factor 1 Long R3 (IGF-1 LR3), also known as Long R3-IGF-1, is a synthetic analog of human insulin-like growth factor 1 (IGF-1). IGF-1 plays a crucial role in regulating growth, development, and metabolism throughout the body. IGF-1 LR3 is designed to have a longer half-life and increased potency compared to natural IGF-1, making it a potential therapeutic agent for various conditions.
When seeking to purchase IGF-1 LR3 online, numerous options are available. However, buying peptides from a randomly chosen company can pose risks.
Unfortunately, many companies selling peptides do not conduct product testing or may conceal certificates and contact details for their third-party labs. This raises concerns about potential undisclosed information.
IGF-1 LR3 FAQs
Some studies suggest that IGF-1 LR3 may enhance cognitive function by increasing brain-derived neurotrophic factor (BDNF) levels. BDNF is a protein involved in the growth and survival of neurons, and it plays a crucial role in memory and learning. However, more research is needed to confirm the cognitive benefits of IGF-1 LR3.
IGF-1 LR3’s ability to stimulate cell proliferation and tissue regeneration may promote faster wound healing. Studies have shown that IGF-1 LR3 can accelerate the healing process in various types of wounds, including skin ulcers and burns.
Yes, IGF-1 LR3 is a naturally occurring variant of IGF-1 that is produced in small amounts in the liver, kidneys, and other tissues. However, the synthetic form of IGF-1 LR3 is more potent and has a longer half-life than the natural form.
IGF-1 LR3 is a promising therapeutic agent with the potential to treat a wide range of conditions. However, more research is needed to confirm its safety and efficacy in humans. If further studies prove to be positive, IGF-1 LR3 could become an essential tool for treating muscle wasting, osteoporosis, diabetes, and other age-related conditions.
IGF-1 LR3 (Insulin-like Growth Factor 1 Long R3) is a synthetic analog of human insulin-like growth factor 1 (IGF-1). It’s designed to have a longer half-life and increased potency compared to natural IGF-1. IGF-1 LR3 plays a crucial role in regulating growth, development, and metabolism throughout the body.
The main differences between regular IGF-1 and Long R3 IGF-1 are:
Structure: IGF-1 LR3 has an arginine substitution at the third amino acid position and an additional 13 amino acids at its N-terminus.Half-life: IGF-1 LR3 has a much longer half-life (approximately 16 hours) compared to natural IGF-1 (about 10 minutes).Potency: IGF-1 LR3 has increased potency due to its enhanced binding affinity to the IGF-1 receptor and reduced binding to IGF binding proteins (IGFBPs).Duration of action: The structural modifications allow IGF-1 LR3 to remain active in the body for a more extended period, potentially increasing its effectiveness.
Why buy IGF-1 LR3 from Sports Technology Labs?
At Sports Technology Labs, you can find the highest quality IGF-1 LR3 for sale anywhere on the internet. When you buy peptides from Sports Technology Labs, you are choosing the highest quality products.
Our IGF-1 LR3, recognized as the purest peptide compound, undergoes thorough testing and certification by accredited American third-party laboratories. These labs readily accept phone calls for certificate verification, ensuring transparency in our product quality.
Your IGF-1 LR3 will be delivered in lyophilized form, securely packaged in glass vials, and refrigerated for stability. At Sports Technology Labs, we prioritize transparency in all business operations, eliminating the need for discreet payment methods and guaranteeing the accuracy of our product representation. We are committed to providing the highest quality IGF-1 LR3 for online purchase, supported by a robust 60-day money-back guarantee.
We offer complimentary shipping on orders exceeding $149, with expedited shipping options for those requiring swift delivery. Subscribers to our email list enjoy a 10% discount, and an additional 10% savings are available for cryptocurrency payments.
Choosing Sports Technology Labs ensures access to premium IGF-1 LR3 online. Our commitment to consistent, verifiable product quality, secure packaging, timely delivery, and exceptional customer service sets us apart.
For any inquiries about IGF-1 LR3 or our other offerings, please contact us, and we’ll promptly address your concerns.
IGF-1 LR3
All Sports Technology Labs peptides are third-party tested by MZ Biolabs, an independent laboratory based in Arizona. While not bottled in the USA, every batch is tested here to verify accuracy and purity. Our Certificates of Analysis confirm that products meet the listed specifications.
Structure and Composition: IGF-1 LR3 differs from natural IGF-1 in two main ways:
Arginine 3 (R3): The third amino acid in the IGF-1 LR3 sequence is arginine (R) instead of glutamic acid (E) in natural IGF-1. This substitution enhances IGF-1 LR3’s binding affinity to the IGF-1 receptor.
N-terminal Extension: IGF-1 LR3 has an additional 13 amino acids at its N-terminus, which extends its half-life and reduces its binding affinity to IGF binding proteins (IGFBPs). IGFBPs regulate the availability and activity of IGF-1, and reduced binding to IGFBPs allows IGF-1 LR3 to remain active for a more extended period.
Extended Half-life
IGF-1 LR3 has a half-life of approximately 16 hours, significantly longer than the rough estimate of 10 minutes of natural IGF-1. This prolonged duration of action allows IGF-1 LR3 to exert its effects more effectively.
Mechanism of Action
IGF-1 LR3 binds to the IGF receptor, triggering a cascade of signaling events that promote growth, development, and metabolism. These effects include:
Cell Proliferation: IGF-1 LR3 stimulates the proliferation of cells involved in muscle growth, bone repair, and tissue regeneration.
Protein Synthesis: IGF-1 LR3 enhances protein synthesis, leading to increased muscle mass and improved tissue function.
Glucose Metabolism: IGF-1 LR3 promotes glucose uptake by cells, improving energy production and reducing blood sugar levels.
Clinical Trials and Efficacy
IGF-1 LR3 is being investigated for its potential therapeutic applications in various medical conditions:
Muscle Wasting: IGF-1 LR3 may help treat muscle loss associated with aging, sarcopenia, and conditions like cancer cachexia
Growth Hormone Deficiency: IGF-1 LR3 could be used to supplement IGF-1 levels in individuals with growth hormone deficiency.
Wound Healing: IGF-1 LR3 may promote faster wound healing by stimulating cell proliferation and tissue regeneration.
This preparation is a research chemical for in vitro laboratory research purposes only by licensed professionals. The FDA does not approve it for any introduction into the human or animal body. IGF-1 LR3 is not a drug, food, supplement, or cosmetic and may not be misbranded, misused, or mislabeled as a drug, food, supplement, or cosmetic.
Scientific Research References:
1. Bailes, J., & Soloviev, M. (2021). Insulin-like growth factor-1 (IGF-1) and its monitoring in medical diagnostics and in sports. Biomolecules, 11(2), 217.
2. Ketha, H., & Singh, R. J. (2015). Clinical assays for quantitation of insulin-like growth factor-1 (IGF-1). Methods, 81, 93-98.
3. Yakar, S., Werner, H., & Rosen, C. J. (2018). 40 YEARS OF IGF-1: Insulin-like growth factors: actions on the skeleton. Journal of molecular endocrinology, 61(1), T115-T137.
4. Thornton, K. J., Kamanga-Sollo, E., White, M. E., & Dayton, W. R. (2016). Active G protein–coupled receptors (GPCR), matrix metalloproteinases 2/9 (mmp2/9), heparin-binding epidermal growth factor (HBEGF), epidermal growth factor receptor (EGFR), ErbB2, and insulin-like growth factor 1 receptor (IGF-1R) are necessary for trenbolone acetate–induced alterations in protein turnover rate of fused bovine satellite cell cultures. Journal of animal science, 94(6), 2332-2343.
5. White, A., Stremming, J., Brown, L. D., & Rozance, P. J. (2023). Attenuated glucose-stimulated insulin secretion during an acute IGF-1 LR3 infusion into fetal sheep does not persist in isolated islets. Journal of Developmental Origins of Health and Disease, 14(3), 353-361.
6. Chakravarthy, M. V. (2000). Modulation of replicative senescence of skeletal muscle satellite cells by insulin-like growth factor-I (IGF-I) (Doctoral dissertation, The University of Texas Graduate School of Biomedical Sciences at Houston).
8. Kyle, A. H., Baker, J. H., & Minchinton, A. I. (2012). Targeting quiescent tumor cells via oxygen and IGF-I supplementation. Cancer research, 72(3), 801-809.
10. Miescher, I., Rieber, J., Calcagni, M., & Buschmann, J. (2023). In Vitro and In Vivo Effects of IGF-1 Delivery Strategies on Tendon Healing: A Review. International Journal of Molecular Sciences, 24(3), 2370.
11. Dyer, A. H., Vahdatpour, C., Sanfeliu, A., & Tropea, D. (2016). The role of Insulin-Like Growth Factor 1 (IGF-1) in brain development, maturation, and neuroplasticity. Neuroscience, 325, 89-99.
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