SARMs and peptides are both of interest to medical researchers for their potential to treat several issues, including insufficient muscle tissue. Unfortunately, it’s not uncommon to confuse the two.
However, there are notable differences between them. So, let’s briefly look at SARMs vs peptides.
How do they work? And what are their potential benefits? Keep reading to find out.
What Are SARMs and Peptides?
SARMs (selective androgen receptor modulators) are synthetic therapeutic compounds. They possess traits similar to anabolic steroids without sharing some undesirable side effects.
SARMs do not occur naturally but are created in laboratories. Further, SARMs are still relegated to research. They do not have Food and Drug Administration (FDA) approval for human consumption.
Peptides are strings of amino acids. The human body makes its own peptides, but they are also found in some foods. Additionally, peptides are made in laboratories.
SARMs vs Peptides: How Do They Work?
SARMs are selective modulators because they only target specific androgen receptors. In contrast, anabolic steroids affect more of the body. They bind androgen receptors throughout the body.
For example, SARMs focus on stimulating receptors to a far greater extent in the desired areas like muscle and bone tissues. At the same time, they have only a mild effect on the prostate.
Peptides can prompt the body to increase its production of specific components. For instance, collagen peptides are responsible for more collagen. Increased collagen can make the skin look and feel healthier.
Similarly, growth hormone-releasing peptides (GHRP) can convince the body to release growth hormones. In turn, more growth hormone production can lead to muscle growth. The peptides target the pituitary and hypothalamic receptors.
What Are Their Potential Benefits?
The medical community has shown interest in the possible use of SARMs to spur the growth of muscle tissue. Most notably, this is useful with patients battling diseases known for wasting muscle. Among such conditions are cancer, kidney, and liver illnesses.
The old-school testosterone treatment for aging men poses a danger to the prostate. Too much testosterone can cause unwanted growth.
That’s why men with enlarged prostates must continually monitor their testosterone levels. So, it’s too risky for them to use additional testosterone to combat the loss of muscle mass.
SARMs are appealing compounds for investigators to evaluate because of their narrow focus. SARMs can target the regrowth of muscle tissue in older men while virtually ignoring the prostate.
SARMs can stimulate bone tissue growth also. Evidence indicates a connection between bone health and androgens.
For example, a loss of androgen is not surprising in older men suffering from a hip fracture. That’s according to research done at Belgium’s Katholieke Universiteit Leuven.
In animal studies, SARMs have shown the ability to increase bone strength. If they prove beneficial in humans, they could provide an alternative method to fight osteoporosis.
Most therapies focus on slowing down the body’s ability to reabsorb bone but not on rebuilding it. SARMs could offer a method to replace missing bone mass.
It is also possible that SARMs could promote faster recovery. They might be delivered in higher dosages than steroidal androgen without fear of dangerous side effects.
If doctors use them against human osteoporosis one day, they might be combined with other treatments. SARMs plus anti-resorptive agents might offer a two-pronged approach.
Researchers continue to look for a safe and effective chemical male contraceptive. Current attempts at chemical contraception include the simultaneous use of testosterone and progestin.
But no one wants the side effects of testosterone treatment. These include enlarged male breasts and weight gain. Unfortunately, testosterone also tends to lower HDL cholesterol while increasing hemoglobin.
One of the advantages of SARMs is their ability to be absorbed by the body orally, making them especially appealing as a possible component of a pill. SARMs may potentially replace traditional testosterone as part of oral male contraception.
Peptides and Medicines
Unlike SARMs, some peptides have the approval of the FDA for human use. So, they appear regularly in various medicines like for example, insulin.
For example, you can find them in treatments for high blood pressure and diabetes. Peptides may also offer an alternative to traditional antibiotics.
Bacteria have grown resistant to a disturbing amount of the antibiotics doctors prescribed through the 20th century. So, it has become imperative that modern researchers find replacements.
Living organisms produce peptides that fight bacteria. These peptides have been the inspiration for trying to produce synthetic versions. The goal is to create even more powerful, more versatile peptides.
Peptides and Growth Hormone
Some synthetic peptides increase the production of the Growth Hormone Releasing Hormone (GHRH). These have been a benefit to science treating children suffering from low levels of GHRH.
In older adults, these same peptides have shown signs of slowing down the aging process connected with muscle mass. It’s natural to lose muscle mass with aging, but peptides can increase muscle growth even in seniors.
Peptides are likely to have few side effects because they have only an indirect impact on muscle growth compared to SARMs. Peptides don’t directly trigger the increase of muscle tissue.
Instead, they signal the body to produce more naturally-occurring growth hormones. It’s the body’s natural growth hormone that then directly influences muscle activity. MK-677 is an orally active compound that replicates the effects of these peptides.
Some peptides as well as MK 677 tend to increase hunger which can work well for those attempting to replace or augment muscle tissue. The additional food intake can provide the body with the components necessary to assist in muscle production.
Peptides are available via several delivery routes suitable for the user and the purpose. Some are available orally, nasally, and sublingually however most peptides are destroyed by gastric secretions and the majority can only be administered via injection.
Where to Purchase SARMs
It’s important to have a trusted source for any research chemical, including SARMs. Sports Technology Labs offer a wide variety of SARMs that undergo third-party testing for purity.
We offer a convenient ordering process plus fast shipping from the United States to international destinations. Free shipping is also available.
If you have additional questions about our products, please contact us today for more information
- Boonen S, Vanderschueren D, Cheng XG, Verbeke G, Dequeker J, Geusens P, Broos P, Bouillon R. Age-related (type II) femoral neck osteoporosis in men: biochemical evidence for both hypovitaminosis D- and androgen deficiency-induced bone resorption. J Bone Miner Res. 1997 Dec;12(12):2119-26. doi: 10.1359/jbmr.19184.108.40.2069. PMID: 9421246.
- Kamischke A, Nieschlag E. Progress towards hormonal male contraception. Trends Pharmacol Sci. 2004 Jan;25(1):49-57. doi: 10.1016/j.tips.2003.11.009. PMID: 14723979.
- Chen, Jiyun et al. “Discovery and therapeutic promise of selective androgen receptor modulators.” Molecular interventions vol. 5,3 (2005): 173-88. doi:10.1124/mi.5.3.7
- Lei, Jun et al. “The antimicrobial peptides and their potential clinical applications.” American journal of translational research vol. 11,7 3919-3931. 15 Jul. 2019
- Deal, Cheri et al. “Growth hormone treatment of Canadian children: results from the GeNeSIS phase IV prospective observational study.” CMAJ open vol. 6,3 E372-E383. 10 Sep. 2018, doi:10.9778/cmajo.20180020